Multiple strategies to activate gold nanoparticles as antibiotics

被引：147
作者：
Zhao, Yuyun [1 ]
Jiang, Xingyu [1 ]
机构：
[1] Natl Ctr NanoSci & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China
来源：
NANOSCALE | 2013年 / 5卷 / 18期
基金：
美国国家科学基金会;
关键词：
PSEUDOMONAS-AERUGINOSA; ANTIBACTERIAL ACTIVITY; IN-VIVO; STAPHYLOCOCCUS-AUREUS; OXIDATIVE STRESS; DRUG; TOXICITY; BACTERIA; SILVER; RESISTANCE;
D O I：
10.1039/c3nr01990j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Widespread antibiotic resistance calls for new strategies. Nanotechnology provides a chance to overcome antibiotic resistance by multiple antibiotic mechanisms. This paper reviews the progress in activating gold nanoparticles with nonantibiotic or antibiotic molecules to combat bacterial resistance, analyzes the gap between experimental achievements and real clinical application, and suggests some potential directions in developing antibacterial nanodrugs.
引用
收藏
页码：8340 / 8350
页数：11
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