SUSPECTS: enabling fast and effective prioritization of positional candidates

被引：170

作者：

Adie, EA ^{[1
]}

Adams, RR ^{[1
]}

Evans, KL ^{[1
]}

Porteous, DJ ^{[1
]}

Pickard, BS ^{[1
]}

机构：

[1] Univ Edinburgh, Med Genet Sect, Sch Mol & Clin Med, Edinburgh EH4 2XU, Midlothian, Scotland

来源：

BIOINFORMATICS | 2006年 / 22卷 / 06期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1093/bioinformatics/btk031

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

SUSPECTS is a web-based server which combines annotation and sequence-based approaches to prioritize disease candidate genes in large regions of interest. It uses multiple lines of evidence to rank genes quickly and effectively while limiting the effect of annotation bias to significantly improve performance.

引用

页码：773 / 774

页数：2

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