Prevalence and Genetic Diversity of Atypical Porcine Pestivirus (APPV) Detected in South Korean Wild Boars

被引:18
作者
Choe, SeEun [1 ]
Park, Gyu-Nam [1 ]
Cha, Ra Mi [1 ]
Hyun, Bang-Hun [1 ]
Park, Bong-Kyun [1 ,2 ]
An, Dong-Jun [1 ]
机构
[1] Anim & Plant Quarantine Agcy, Virus Dis Div, Gimchen 39660, Gyeongbuk Do, South Korea
[2] Univ Seoul, Coll Vet Med, Seoul 08826, South Korea
来源
VIRUSES-BASEL | 2020年 / 12卷 / 06期
关键词
APPV; wild boar; ML tree; Clade; pestivirus; PIGS;
D O I
10.3390/v12060680
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Atypical porcine pestivirus (APPV), currently classified aspestivirus K, causes congenital tremor (CT) type A-II in piglets. Eighteen APPV strains were identified from 2297 South Korean wild boars captured in 2019. Phylogenetic analysis of the structural protein E2 and nonstructural proteins NS3 and Npro classified the APPV viruses, including reference strains, into Clades I, II and III. Clade I was divided into four subclades; however, the strains belonging to the four subclades differed slightly, depending on the tree analysis, the NS3, E2, and Npro genes. The maximum-likelihood method was assigned to South Korean wild boar APPV strains to various subclades within the three trees: subclades I.1 and I.2 in the E2 tree, subclade I.1 in the Npro tree, and subclades I.1 and I.4 in the NS3 ML tree. In conclusion, APPV among South Korean wild boars belonging to Clade I may be circulating at a higher level than among the South Korean domestic pig populations.
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页数:10
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