Hypocholesterolaemic effect of the oleoresin of Capsicum annum L. in gerbils (Meriones hurrianae Jerdon)

被引：12

作者：

Gupta, RS ^{[1
]}

Dixit, VP

Dobhal, MP

机构：

[1] Univ Rajasthan, Dept Zool, Jaipur 302004, Rajasthan, India

[2] Univ Rajasthan, Dept Chem, Jaipur 302004, Rajasthan, India

来源：

PHYTOTHERAPY RESEARCH | 2002年 / 16卷 / 03期

关键词：

Capsicum annum oleoresin; cholesterol; triglycerides; gerbils;

D O I：

10.1002/ptr.824

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The effect of capsicum oleoresin (CO) on dietary hypercholeterolaemia were observed in male gerbils at a dose of 75 mg/kg body wt/day. The oleoresin reduced serum cholesterol and triglycerides by 70% and 66%, whereas, liver cholesterol and triglycerides were lowered by 70.9% and 68.7% respectively, in comparison with atherogenic fed controls. CO feeding prevented the accumulation of cholesterol and triglycerides in the liver and aorta. The faecal excretion of cholesterol and triglycerides were significantly increased in oleoresin fed gerbils. Copyright (C) 2002 John Wiley Sons, Ltd.

引用

页码：273 / 275

页数：3

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