Peculiarities of the Functional State of Mitochondria of Peripheral Blood Leukocytes in Patients with Acute Myocardial Infarction

被引：3

作者：

Afanas'ev, S. A. ^{[1
]}

Muslimova, E. F. ^{[1
]}

Rebrova, T. Yu. ^{[1
]}

Tsapko, L. P. ^{[1
]}

Kercheva, M. A. ^{[1
]}

Golubenko, M. V. ^{[2
]}

机构：

[1] Russian Acad Sci, Cardiol Res Inst, Tomsk Natl Res Med Ctr, Tomsk, Russia

[2] Russian Acad Sci, Res Inst Med Genet, Tomsk Natl Res Med Ctr, Tomsk, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2020年 / 169卷 / 04期

关键词：

acute myocardial infarction; mitochondria; oxidative phosphorylation; DNA;

D O I：

10.1007/s10517-020-04903-9

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We studied the rate of oxygen consumption by mitochondria isolated from peripheral blood leukocytes of patients with acute myocardial infarction and healthy volunteers. It was found that leukocyte mitochondria in patients with acute myocardial infarction were characterized by significantly lower rate of oxygen consumption and lower level of coupling of oxidation and phosphorylation processes in comparison with mitochondria from healthy volunteers.

引用

页码：435 / 437

页数：3

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