Combined tetraphenylethylene fluorogens with positive charge for imaging capsule-covered pathogens

被引：8

作者：

Ai, Wenting ^{[1
]}

Yang, Zhiqiang ^{[2
]}

Ma, Yufan ^{[1
]}

Han, Xiaomin ^{[1
]}

Chen, Yuzhi ^{[1
]}

Zhu, Kui ^{[2
]}

Wang, Zhuo ^{[1
]}

机构：

[1] Beijing Univ Chem Technol, Coll Chem, Beijing Adv Innovat Ctr Soft Matter Sci & Engn, State Key Lab Chem Resource Engn, Beijing 100029, Peoples R China

[2] China Agr Univ, Coll Vet Med, Beijing Adv Innovat Ctr Food Nutr & Human Hlth, Beijing 100193, Peoples R China

来源：

ANALYST | 2020年 / 145卷 / 20期

基金：

北京市自然科学基金;

关键词：

KLEBSIELLA-PNEUMONIAE; AIE; PROBES;

D O I：

10.1039/d0an00349b

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Capsule-covered pathogens can cause serious infectious diseases, and are highly pathogenic to humans. Herein, we developed four positively charged tetraphenylethylene derivatives (PC-TPEgens) that in certain combinations were applied to identify capsule-bearing pathogens using fluorescence imaging. The dual-charged probes were used to visualize the entire process of phagocytosis of pathogens into macrophages.

引用

页码：6435 / 6440

页数：6

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