Total synthesis of rubrolide M and some of its unnatural congeners

被引：61

作者：

Bellina, F ^{[1
]}

Anselmi, C ^{[1
]}

Rossi, R ^{[1
]}

机构：

[1] Dipartimento Chim & Chim Ind, I-56126 Pisa, Italy

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 11期

关键词：

D O I：

10.1016/S0040-4039(02)00202-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two protocols have been developed for the Pd-catalyzed regioselective synthesis of 4-aryl-3-chloro-2(5H)-furanones starting from 3,4-dichloro-2(5H)-furanone. These monochloro derivatives have then been used as precursors to (Z)-4-aryl-5-[I(aryl)methylidenel-3-chloro-2(5H)-furanones including naturally-occurring rubrolide M. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：2023 / 2027

页数：5

共 13 条

[11] New rubrolides from the ascidian Synoicum blochmanni [J].