Detection of Pb2+ in Aqueous Solution by Using a DNA-modified Microcantilever

被引：0

作者：

Peng, Rong-Peng ^{[1
,2
,3
,4
]}

Xing, Ling-Bao ^{[1
,2
]}

Wang, Xiao-Jun ^{[1
,2
]}

Wu, Cheng-juan ^{[1
,2
]}

Chen, Bin ^{[1
,2
]}

Ji, Hai-Feng ^{[4
]}

Wu, Li-Zhu ^{[1
,2
]}

Tung, Chen-Ho ^{[1
,2
]}

机构：

[1] Chinese Acad Sci, Tech Inst Phys & Chem, Key Lab Photochem Convers & Optoelect Mat, Beijing 100190, Peoples R China

[2] Chinese Acad Sci, Grad Univ, Beijing 100190, Peoples R China

[3] Nanchang Univ, Coll Chem, Nanchang 330031, Jiangxi, Peoples R China

[4] Drexel Univ, Dept Chem, Philadelphia, PA 19010 USA

来源：

ANALYTICAL SCIENCES | 2016年 / 32卷 / 10期

基金：

美国国家科学基金会;

关键词：

Lead ion; detection; microcantilever; sensor; DNA; GOLD NANOPARTICLES; LEAD(II) ION; DNAZYME; FLUORESCENCE; SENSOR; CHEMOSENSORS; SPECTROMETRY; ADSORPTION; PORPHYRINS; BIOSENSOR;

D O I：

10.2116/analsci.32.1065

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

We developed a novel Pb2+-sensor based on a microcantilever that was modified with a specific Pb2+-dependent DNAzyme molecule. This microcantilever sensor could detect Pb2+ sensitively and selectively in an aqueous solution. Upon complexation with Pb2+, the DNAzyme duplex unwinded and formed a G-quadruplex conformation, which led to an increase of repulsion between the DNAzyme molecules and a subsequent bending of the microcantilever. This microcantilever sensor could be regenerated, flowing through a strong Pb2+ chelator, 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid. The detection limit of the microcantilever sensor for Pb2+ ions is as low as 10(-8) M. The microcantilever sensor also exhibited a high selectivity to Pb2+ over other metal ions such as Mg2+, Fe+, Zn2+, Ca2+, and Cd2+.

引用

页码：1065 / 1069

页数：5

共 42 条

[1] Simultaneous generation of hydrides of bismuth, lead and tin in the presence of ferricyanide and application to determination in biominerals by ICP-AES [J].

Afonso, Domingos D. ;

Baytak, Sitki ;

Arslan, Zikri .

JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY, 2010, 25 (05) :726-729

[2]

[Anonymous], 2018, Guidelines for Drinking Water Quality

[3] PB(II)-CATALYSED CLEAVAGE OF THE SUGAR-PHOSPHATE BACKBONE OF YEAST TRANSFER RNAPHE - IMPLICATIONS FOR LEAD TOXICITY AND SELF-SPLICING RNA [J].

BROWN, RS ;

HINGERTY, BE ;

DEWAN, JC ;

KLUG, A .

NATURE, 1983, 303 (5917) :543-546

[4] PROTONATION AND METAL COMPLEXATION STUDIES ON SOME OXA-DIAZA-MACROCYCLIC LIGANDS [J].

CABRAL, MF ;

COSTA, J ;

DELGADO, R ;

DASILVA, JJRF ;

VILHENA, MF .

POLYHEDRON, 1990, 9 (23) :2847-2857

[5] ADSORPTION-INDUCED SURFACE STRESS AND ITS EFFECTS ON RESONANCE FREQUENCY OF MICROCANTILEVERS [J].

CHEN, GY ;

THUNDAT, T ;

WACHTER, EA ;

WARMACK, RJ .

JOURNAL OF APPLIED PHYSICS, 1995, 77 (08) :3618-3622

[6] CHEMICAL COMMUNICATION IN WATER USING FLUORESCENT CHEMOSENSORS [J].

CZARNIK, AW .

ACCOUNTS OF CHEMICAL RESEARCH, 1994, 27 (10) :302-308

[7] Immobilization of DNAzyme catalytic beacons on PMMA for Pb2+ detection [J].

Dalavoy, Tulika S. ;

Wernette, Daryl P. ;

Gong, Maojun ;

Sweedler, Jonathan V. ;

Lu, Yi ;

Flachsbart, Bruce R. ;

Shannon, Mark A. ;

Bohn, Paul W. ;

Cropek, Donald M. .

LAB ON A CHIP, 2008, 8 (05) :786-793

[8] Graphene Quantum Dots/L-Cysteine Coreactant Electrochemiluminescence System and Its Application in Sensing Lead(II) Ions [J].

Dong, Yongqiang ;

Tian, Wanrong ;

Ren, Shuyan ;

Dai, Ruiping ;

Chi, Yuwu ;

Chen, Guonan .

ACS APPLIED MATERIALS & INTERFACES, 2014, 6 (03) :1646-1651

[9] A DNAzyme cascade for the amplified detection of Pb2+ ions or L-histidine [J].

Elbaz, Johann ;

Shlyahovsky, Bella ;

Willner, Itamar .

CHEMICAL COMMUNICATIONS, 2008, (13) :1569-1571

[10] Cloud point extraction and flame atomic absorption spectrometric determination of cadmium(II), lead(II), palladium(II) and silver(I) in environmental samples [J].

Ghaedi, Mehrorang ;

Shokrollahi, Ardeshir ;

Niknam, Khodabakhsh ;

Niknam, Ebrahim ;

Najibi, Asma ;

Soylak, Mustafa .

JOURNAL OF HAZARDOUS MATERIALS, 2009, 168 (2-3) :1022-1027

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