Reaction between enaminones and acetylenic esters in the presence of triphenylphosphine: a convenient synthesis of alkyl 2(1-benzyl-2,4-dioxo-2,3,4,5,6,7-hexahydro-1H-indol-3-yl)acetates

被引:12
作者
Nasiri, Farough [1 ]
Bayzidi, Massood [2 ]
Zolali, Amin [2 ]
机构
[1] Univ Mohaghegh Ardabili, Dept Appl Chem, Fac Sci, Ardebil, Iran
[2] Univ Kurdistan, Dept Chem, Fac Sci, Sanandaj, Iran
关键词
beta-Enaminones; Dialkyl acetylenedicarboxylates; Triphenylphosphine; One-pot reaction; ONE-POT SYNTHESIS; DIALKYL ACETYLENEDICARBOXYLATES; FACILE SYNTHESIS; DIMETHYL ACETYLENEDICARBOXYLATE; STEREOSELECTIVE REACTION; MULTICOMPONENT REACTIONS; ACTIVATED ACETYLENES; ISOCYANIDES; DERIVATIVES; DIBENZOYLACETYLENE;
D O I
10.1007/s11030-012-9389-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
One-pot reaction between enaminocarbonyl compounds derived from six-membered 1,3-diketones and substituted benzylamines, and electron-deficient acetylenic esters in the presence of triphenylphosphine lead to alkyl 2-(1-benzyl-6,6-dimethyl-2,4-dioxo-2,3,4,5,6,7-hexahydro-1H-indol-3-yl)acetate derivatives in good yields.
引用
收藏
页码:619 / 623
页数:5
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