Pediatric mucosa-associated lymphoid tissue (MALT) lymphoma of lip: a case report and literature review

被引：15

作者：

Ryu, MiHeon ^{[2
]}

Han, SeonHui ^{[1
]}

Che, ZhongMin ^{[1
]}

Min, YonSook ^{[3
]}

Yoo, Keon Hee ^{[4
]}

Koo, Hong Hoe ^{[4
]}

Yang, Woo-Ick ^{[5
]}

Kim, Hyun Sil ^{[1
]}

机构：

[1] Yonsei Univ, Coll Dent, Oral Canc Res Inst, Dept Oral Pathol, Seoul 120752, South Korea

[2] Namseoul Univ, Dept Dent Hyg, Seoul, South Korea

[3] Yonsei Univ, Coll Dent, Dept Oral & Maxillofacial Surg, Seoul 120752, South Korea

[4] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pediat, Seoul, South Korea

[5] Yonsei Univ, Coll Dent, Dept Pathol, Seoul 120752, South Korea

来源：

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY | 2009年 / 107卷 / 03期

关键词：

MINOR SALIVARY-GLAND; B-CELL LYMPHOMA; CHILDREN;

D O I：

10.1016/j.tripleo.2008.10.013

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Mucosa-associated lymphoid tissue (MALT) lymphoma is listed in the new World Health Organization classification as extranodal marginal zone B-cell lymphoma of MALT. Most cases occur predominantly in adults and are rare in children or adolescents. We report, with a review of earlier literature, a MALT lymphoma of the lower lip in a 7-year-old immunocompetent child. The patient had a sessile, indurated, and firm mass on the lower lip without regional lymphadenopathy. Microscopically, dense lymphoid cell infiltrates composed of small- to medium-sized centrocyte-like cells and plasmacytoid cells infiltrating around scattered reactive germinal centers were observed, with formation of typical lymphoepithelial lesions. Immunohistochemical staining demonstrated positivity of atypical lymphoid cells for CD20, CD43, CD79a, and Bcl-2 and negativity for CD3, CD5, CD10, CD23, Ki-1, Bcl-10, and ALK. Cytoplasmic kappa light chain restriction was demonstrated. We conclude that this case represents the youngest patient with a MALT lymphoma of the lip. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009;107:393-397)

引用

页码：393 / 397

页数：5

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