Endothelial Fatty Acid Transport: Role of Vascular Endothelial Growth Factor B

被引：60

作者：

Hagberg, Carolina ^{[1
]}

Mehlem, Annika ^{[1
]}

Falkevall, Annelie ^{[1
]}

Muhl, Lars ^{[1
]}

Eriksson, Ulf ^{[1
]}

机构：

[1] Karolinska Inst, Stockholm, Sweden

来源：

PHYSIOLOGY | 2013年 / 28卷 / 02期

关键词：

VEGF-B; INSULIN-RESISTANCE; BINDING PROTEIN; METABOLIC-RESPONSES; TARGETED DELETION; LIPID-METABOLISM; TYROSINE KINASE; CELLULAR UPTAKE; CD36; MOUSE;

D O I：

10.1152/physiol.00042.2012

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Dietary lipids present in the circulation have to be transported through the vascular endothelium to be utilized by tissue cells, a vital mechanism that is still poorly understood. Vascular endothelial growth factor B (VEGF-B) regulates this process by controlling the expression of endothelial fatty acid transporter proteins (FATPs). Here, we summarize research on the role of the vascular endothelium in nutrient transport, with emphasis on VEGF-B signaling.

引用

页码：125 / 134

页数：10

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