Multidrug-Resistant Tuberculosis (TB) Resistant to Fluoroquinolones and Streptomycin but Susceptible to Second-Line Injection Therapy Has a Better Prognosis than Extensively Drug-Resistant TB

被引：20
作者：
Chan, Edward D. [1 ,3 ,4 ,5 ,6 ]
Strand, Matthew J. [9 ]
Iseman, Michael D. [1 ,2 ,5 ,6 ,7 ,8 ]
机构：
[1] Univ Colorado, Dept Med, Denver, CO USA
[2] Univ Colorado, Natl Jewish Hlth, Dept Med, Denver, CO 80206 USA
[3] Univ Colorado, Cell Biol Program, Natl Jewish Hlth, Denver, CO 80202 USA
[4] Univ Colorado, Denver Vet Adm Med Ctr, Denver, CO 80202 USA
[5] Univ Colorado, Div Pulm Sci, Denver, CO 80202 USA
[6] Univ Colorado, Div Crit Care Med, Denver, CO 80202 USA
[7] Univ Colorado, Div Infect Dis, Denver, CO 80202 USA
[8] Univ Colorado, Hlth Sci Ctr, Denver, CO USA
[9] Univ Colorado, Natl Jewish Hlth, Div Biostat, Denver, CO 80206 USA
来源：
CLINICAL INFECTIOUS DISEASES | 2009年 / 48卷 / 05期
关键词：
TREATMENT OUTCOMES;
D O I：
10.1086/597010
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Multidrug-resistant tuberculosis (TB) strains resistant to the fluoroquinolones and streptomycin but susceptible to second-line injection treatment would not be defined as extensively drug-resistant TB. In a cohort of 174 patients with multidrug-resistant TB, we demonstrated that 12 patients with multidrug-resistant TB strains resistant to the fluoroquinolones and streptomycin had significantly better initial and long-term outcomes, compared with 10 patients with extensively drug-resistant TB.
引用
收藏
页码：E50 / E52
页数：3
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