Divalproex sodium: Migraine treatment and monitoring

被引:17
作者
Silberstein, SD
Wilmore, LJ
机构
[1] TEMPLE UNIV,SCH MED,PHILADELPHIA,PA 19122
[2] UNIV TEXAS,SCH MED,HOUSTON,TX
来源
HEADACHE | 1996年 / 36卷 / 04期
关键词
divalproex sodium; migraine; hepatotoxicity;
D O I
10.1046/j.1526-4610.1996.3604239.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Divalproex sodium is an effective drug for the treatment of migraine. Most adverse drug events are transient and not of great clinical concern. Although rare, well-documented examples of liver toxicity have been reported in children under 2 years of age on polypharmacy. Additional cases occur in children under 10 who are receiving polypharmacy, particularly those who have intractable seizures and degenerative central nervous system disease. Clinicians who treat migraineurs with divalproex sodium do not need to be overly preoccupied with monitoring of drug levels and liver function tests. The most valuable test is clinical observation of the patient.
引用
收藏
页码:239 / 242
页数:4
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