Copper-catalyzed three-component one-pot synthesis of quinazolines

被引：53
|
作者：
Ju, Jia [1 ]
Hua, Ruimao [1 ,2 ]
Su, Ji [1 ]
机构：
[1] Tsinghua Univ, Dept Chem, Key Lab Organ Optoelect & Mol Engn, Minist Educ, Beijing 100084, Peoples R China
[2] Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China
来源：
TETRAHEDRON | 2012年 / 68卷 / 46期
基金：
中国国家自然科学基金;
关键词：
Ammonia water; ortho-Bromo aromatic ketones; ortho-Bromo aromatic aldehydes; Aromatic aldehydes; Primary alcohols; Quinazolines; O-PHENYL OXIMES; 2-SUBSTITUTED QUINAZOLINES; DERIVATIVES; 2-PHENYLQUINAZOLINES; INHIBITORS;
D O I：
10.1016/j.tet.2012.09.035
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Two efficient approaches to multi-substituted quinazolines by the three-component one-pot reaction of o-bromo aromatic ketones/aldehydes, ammonia water and aromatic aldehydes, or primary alcohols catalyzed by CuCl have been developed. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码：9364 / 9370
页数：7
相关论文
共 50 条
  • [1] Copper-Catalyzed One-Pot, Three-Component Synthesis of Imidazo[1,2-c]quinazolines and Benzimidazo[1,2-c]quinazolines
    Nandwana, Nitesh K.
    Bhawani
    Shinde, Vikki N.
    Kumar, Anil
    CHEMISTRYSELECT, 2021, 6 (43): : 12205 - 12208
  • [2] One-Pot Copper-Catalyzed Three-Component Synthesis of Quinoxalines by Condensation and C-N Bond Formation
    Yuan, Hua
    Li, Kangning
    Chen, Yongxin
    Wang, Yu
    Cui, Jiaojiao
    Chen, Baohua
    SYNLETT, 2013, 24 (17) : 2315 - 2319
  • [3] Copper-Catalyzed One-Pot Three-Component Aminophosphinoylation of 1,4-Naphthoquinone
    Wang, Bin
    Han, Wancang
    Zhang, Yonghong
    Chen, Ziren
    Xia, Yu
    Wu, Shaofeng
    Xue, Fei
    Jin, Weiwei
    Liu, Chenjiang
    CHEMISTRYSELECT, 2024, 9 (27):
  • [4] A Selective Three-Component, One-Pot Approach for the Synthesis of 1,2-Dihydroquinazolines and Quinazolines
    Dayakar, Cherupally
    Raju, BhimapakaChina
    CHEMISTRYSELECT, 2018, 3 (32): : 9388 - 9392
  • [5] Palladium-Catalyzed Three-Component Tandem Process: One-Pot Assembly of Quinazolines
    Hu, Kun
    Zhen, Qianqian
    Gong, Julin
    Cheng, Tianxing
    Qi, Linjun
    Shao, Yinlin
    Chen, Jiuxi
    ORGANIC LETTERS, 2018, 20 (10) : 3083 - 3087
  • [6] One-pot three-component synthesis of quinazolines via a copper-catalysed oxidative amination reaction
    Duan, Tiantian
    Zhai, Tianran
    Liu, Huanhuan
    Yan, Zilong
    Zhao, Yue
    Feng, Lei
    Ma, Chen
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2016, 14 (27) : 6561 - 6567
  • [7] A new and facile CuCl2•2H2O-catalyzed one-pot three-component synthesis for quinazolines
    Saad, Syed Muhammad
    Khan, Khalid Mohammed
    Perveen, Shahnaz
    Voelter, Wolfgang
    Taha, Muhammad
    MONATSHEFTE FUR CHEMIE, 2015, 146 (11): : 1877 - 1880
  • [8] Copper-Catalyzed Three-Component Tandem Cyclization for One-Pot Synthesis of Indole-Benzofuran Bis-Heterocycles
    Ma, Peng
    Wang, Yuhang
    Wang, Jianhui
    JOURNAL OF ORGANIC CHEMISTRY, 2024, 89 (23) : 17168 - 17175
  • [9] Synthesis of Benzothiazoles through Copper-Catalyzed One-Pot Three-Component Reactions with Use of Sodium Hydrosulfide as a Sulfur Surrogate
    Park, Namjin
    Heo, Yumi
    Kumar, Manian Rajesh
    Kim, Yong
    Song, Kwang Ho
    Lee, Sunwoo
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2012, 2012 (10) : 1984 - 1993
  • [10] One-pot copper-catalyzed three-component reaction: a modular approach to functionalized 2-quinolones
    Kim, Ah Reum
    Lim, Hee Nam
    RSC ADVANCES, 2020, 10 (13) : 7855 - 7866
12345