Copper-catalyzed three-component one-pot synthesis of quinazolines

被引：55

作者：

Ju, Jia ^{[1
]}

Hua, Ruimao ^{[1
,2
]}

Su, Ji ^{[1
]}

机构：

[1] Tsinghua Univ, Dept Chem, Key Lab Organ Optoelect & Mol Engn, Minist Educ, Beijing 100084, Peoples R China

[2] Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China

来源：

TETRAHEDRON | 2012年 / 68卷 / 46期

基金：

中国国家自然科学基金;

关键词：

Ammonia water; ortho-Bromo aromatic ketones; ortho-Bromo aromatic aldehydes; Aromatic aldehydes; Primary alcohols; Quinazolines; O-PHENYL OXIMES; 2-SUBSTITUTED QUINAZOLINES; DERIVATIVES; 2-PHENYLQUINAZOLINES; INHIBITORS;

D O I：

10.1016/j.tet.2012.09.035

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two efficient approaches to multi-substituted quinazolines by the three-component one-pot reaction of o-bromo aromatic ketones/aldehydes, ammonia water and aromatic aldehydes, or primary alcohols catalyzed by CuCl have been developed. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：9364 / 9370

页数：7

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