Carboxymethyl chitin/organic rectorite composites based nanofibrous mats and their cell compatibility

被引:21
作者
Xin, Shangjing [1 ,2 ]
Li, Yuejun [3 ]
Li, Wei [1 ,2 ]
Du, Jing [1 ,2 ]
Huang, Rong [1 ,2 ]
Du, Yumin [4 ]
Deng, Hongbing [1 ,2 ,4 ]
机构
[1] Huazhong Agr Univ, Coll Food Sci & Technol, Wuhan 430070, Peoples R China
[2] Huazhong Agr Univ, MOE Key Lab Environm Correlat Dietol, Wuhan 430070, Peoples R China
[3] Fourth Mil Med Univ, Dept Plast Surg, Tangdu Hosp, Xian 710038, Peoples R China
[4] Wuhan Univ, Dept Environm Sci, Coll Resource & Environm Sci, Wuhan 430079, Peoples R China
基金
中国国家自然科学基金;
关键词
Carboxymethyl chitin; Poly (vinyl alcohol); Organic rectorite; Nanofibrous mats; Cell compatibility; CHITIN; CHITOSAN; NANOCOMPOSITES; SCAFFOLDS; FILMS;
D O I
10.1016/j.carbpol.2012.06.045
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
In this study, carboxymethyl chitin (CMC) - organic rectorite (OREC)/poly (vinyl alcohol) (PVA) composite nanofibrous mats were successfully prepared via electrospinning. SAXRD pattern showed that the interlayer distance of OREC was increased from 3.68 to 4.08 nm, which verified that polymer chains were intercalated into the interlayer of OREC. Field emission scanning electron microscopy, Fourier transform infrared spectra and energy-dispersive X-ray spectroscopy were used to characterize the morphology and microcosmic structure of nanofibrous mats. Thermal properties of mats were determined by differential scanning calorimetry. To evaluate the cell compatibility of mats, mouse lung fibroblast (L929) was chosen for cell attachment and spreading assay. The results shows that nanofibrous mats contained OREC have better thermal properties. Besides, the addition of OREC has little effect on the cell compatibility of nanofibrous mats. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1069 / 1074
页数:6
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