Highly potent antimicrobial peptide derivatives of bovine cateslytin

被引：6
作者：
Postma, T. M. [1 ]
Liskamp, R. M. J. [1 ]
机构：
[1] Univ Glasgow, Sch Chem, Joseph Black Bldg,Univ Ave, Glasgow G12 8QQ, Lanark, Scotland
来源：
RSC ADVANCES | 2016年 / 6卷 / 97期
关键词：
CHROMOGRANIN-A; ACINETOBACTER-BAUMANNII; COLISTIN RESISTANCE; TRYPTOPHAN-RICH; BAD BUGS; ANTIBACTERIAL; MEMBRANES; HYDROPHOBICITY; MECHANISMS; CHEMISTRY;
D O I：
10.1039/c6ra17944d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Antimicrobial peptides are potentially valuable antibiotics. More research is required to turn these compounds into viable therapeutics. Herein, a novel highly potent antimicrobial peptide is presented as a tool to study antimicrobial peptides. Antibacterial activity in the low micromolar range, low haemolytic activity and excellent serum stability were observed.
引用
收藏
页码：94840 / 94844
页数：5
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