Craniofacial and intracranial manifestations of Langerhans cell histiocytosis: Report of findings in 100 patients

被引：80

作者：

D'Ambrosio, Nicholas ^{[1
,2
]}

Soohoo, Stephanie ^{[2
]}

Warshall, Craig ^{[2
]}

Johnson, Alan ^{[2
]}

Karimi, Sasan ^{[1
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Dept Radiol, New York, NY 10065 USA

[2] Schneider Childrens Hosp, Long Isl Jewish Med Ctr, Dept Radiol, New Hyde Pk, NY 11040 USA

来源：

AMERICAN JOURNAL OF ROENTGENOLOGY | 2008年 / 191卷 / 02期

关键词：

craniofacial; intracranial; Langerhans cell histiocytosis;

D O I：

10.2214/AJR.07.3573

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

OBJECTIVE. The purpose of this study was to review the craniofacial and intracranial clinical and radiologic manifestations of patients diagnosed with Langerhans cell histiocytosis (LCH). This report will compare the frequency of the various manifestations found in our series with those reported in the medical literature. CONCLUSION. In LCH, involvement of the calvaria, skull base, maxillofacial bones, and hypothalamic-pituitary axis is fairly common. The precise location of these lesions contributes to the variety of clinical manifestations of LCH, which includes scalp and/or facial swelling, seizures, hearing loss, recurrent otitis media, gingival bleeding, proptosis, diabetes insipidus, and cranial nerve palsies.

引用

页码：589 / 597

页数：9