RNA polymerase II structure, and organization of the preinitiation complex

被引：36
作者：
Asturias, FJ [1 ]
机构：
[1] Scripps Res Inst, Dept Cell Biol, La Jolla, CA 92037 USA
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 2004年 / 14卷 / 02期
关键词：
D O I：
10.1016/j.sbi.2004.03.007
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Recent X-ray and cryo-electron microscopy studies have provided information about the basal eukaryotic transcription machinery and about Mediator, the complex involved in transcription regulation during initiation. On the basis of this structural information, a model describing the minimal transcription complex and its interaction with Mediator has been proposed. The model provides insight into the possible mechanisms of transcription initiation and regulation.
引用
收藏
页码：121 / 129
页数：9
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