Intracellular zinc irritates TRPA1

被引：11

作者：

Banke, Tue G. ^{[1
]}

Wickenden, Alan D. ^{[1
]}

机构：

[1] Johnson & Johnson Pharmaceut Res & Dev LLC, San Diego, CA 92121 USA

来源：

NATURE CHEMICAL BIOLOGY | 2009年 / 5卷 / 03期

关键词：

D O I：

10.1038/nchembio0309-141

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Exposure to zinc can cause pain and inflammation and can be harmful to human health. New evidence suggests that activation of the irritant receptor, TRPA1, which is expressed on pain-sensing neurons, may be responsible for some of these symptoms of zinc toxicity.

引用

页码：141 / 142

页数：3

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