New SPECT and PET Radiopharmaceuticals for Imaging Inflammatory Diseases: A Meta-analysis of the Last 10 Years

被引：20
作者：
Pacilio, Marta [1 ]
Lauri, Chiara [1 ,2 ]
Prosperi, Daniela [1 ]
Petitti, Agnese [1 ]
Signore, Alberto [1 ,2 ]
机构：
[1] Sapienza Univ Rome, Dept Med Surg Sci & Translat Med, Nucl Med Unit, Rome, Italy
[2] Univ Groningen, Univ Med Ctr Groningen, Dept Nucl Med & Mol Imaging, Groningen, Netherlands
来源：
SEMINARS IN NUCLEAR MEDICINE | 2018年 / 48卷 / 03期
关键词：
SOMATOSTATIN RECEPTOR SCINTIGRAPHY; THYROID EYE DISEASE; IN-VIVO DETECTION; POSITRON-EMISSION-TOMOGRAPHY; RHEUMATOID-ARTHRITIS; GRAVES-OPHTHALMOPATHY; MONOCLONAL-ANTIBODIES; ACTIVATED LYMPHOCYTES; CROHNS-DISEASE; TC-99M-ANTI-TNF-ALPHA SCINTIGRAPHY;
D O I：
10.1053/j.semnuclmed.2017.12.004
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Modem molecular nuclear medicine is rapidly developing in the field of imaging of chronic inflammatory diseases, and many new radiophamiaceuticals have been recently described and tested in animals and man. These can detect early pathophysiological changes before the development of anatomical changes and, often, before clinical onset of symptoms. This field includes new radiopharmaceuticals for SPECT and PET use to define new strategies for imaging immune cells as well as tissue modifications induced by the inflammatory process. In this review, we present the results of a meth-analysis based on radiopharmaceuticals (for SPECT or PET) that are not commercially available and that have been used, at least once, in humans in the last 10 years. (C) 2018 Elsevier Inc. All rights reserved.
引用
收藏
页码：261 / 276
页数：16
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