Electrophysiologic characterization in spinocerebellar ataxia 17

被引：12

作者：

Manganelli, F

Perretti, A

Nolano, M

Lanzillo, B

Bruni, AC

De Michele, G

Filla, A

Santoro, L

机构：

[1] Univ Naples Federico II, Dipartimento Sci Neurol, I-80131 Naples, Italy

[2] IRCCS, Ctr Telese Terme, Salvatore Maugeri Fdn, Telese Terme, Italy

[3] Reg Neurogenet Ctr, Lamezia Terme, Italy

来源：

NEUROLOGY | 2006年 / 66卷 / 06期

关键词：

D O I：

10.1212/01.wnl.0000203514.92781.fd

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors performed a multimodal electrophysiologic evaluation in nine patients belonging to four SCA17 ( spinocerebellar ataxia type 17) families. Peripheral nerve and visual system were not involved. Brainstem auditory evoked potentials were constantly abnormal with central type lesions. Magnetic motor evoked potentials were abnormal only in the lower limbs, suggesting a length-dependent involvement of the pyramidal tract. Somatosensory evoked potentials were abnormal in almost all our patients, and abnormalities were consistent with a somatosensory pathway involvement along the brainstem.

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页码：932 / 934

页数：3

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