19-VNTR loci used in genotyping Chinese clinical Mycobacterium tuberculosis complex strains and in association with spoligotyping

被引：6
作者：
Jiang, Yi [1 ]
Liu, Hai-can [1 ]
Zheng, Huajun [2 ]
Dou, Xiangfeng [3 ]
Tang, Biao [2 ]
Zhao, Xiu-qin [1 ]
Zhu, Yongqiang [2 ]
Lu, Bing [1 ]
Wang, Shengyue [2 ]
Dong, Hai-yan [1 ]
Zhang, Yuan-yuan [1 ]
Zhao, Guoping [2 ]
Wan, Kanglin [1 ]
机构：
[1] Chinese Ctr Dis Control & Prevent, Natl Inst Communicable Dis Control & Prevent, State Key Lab Infect Dis Prevent & Control, Beijing 102206, Peoples R China
[2] Chinese Natl Human Genome Ctr Shanghai, Shanghai MOST Key Lab Hlth & Dis Genom, Shanghai, Peoples R China
[3] Beijing Ctr Dis Prevent & Control, Beijing, Peoples R China
来源：
JOURNAL OF BASIC MICROBIOLOGY | 2013年 / 53卷 / 07期
关键词：
Mycobacterium tuberculosi; VNTR; VARIABLE-NUMBER; TANDEM REPEATS; BEIJING FAMILY; REPETITIVE UNITS; DRUG-RESISTANT; DIFFERENTIATION; UTILITY; IDENTIFICATION; COMBINATION; DIVERSITY;
D O I：
10.1002/jobm.201200230
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Recently, tandem repeat typing has emerged as a rapid and easy method for the molecular epidemiology of the Mycobacterium tuberculosis (M. tuberculosis) complex. In this study, a collection of 19 VNTRs incorporating 15 previously described loci and 4 newly evaluated markers were used to genotype 206 Chinese M. tuberculosis isolates and 9 BCG strains. The discriminatory power was evaluated and compared with that obtained by Spoligotyping. It turned out that 15-locus VNTR could be very useful in M. tuberculosis complex strains genotyping in China. The 4 newly evaluated loci were proved informative and could be useful for future epidemiology studies, especially in Beijing family strains. In addition, a unique pattern of the latter 4 loci were found in Chinese BCG strains.
引用
收藏
页码：562 / 580
页数：19
相关论文
共 31 条
[21]   Identification of possible loci of variable number of tandem repeats in Mycobacterium tuberculosis [J].
Smittipat, N ;
Palittapongarnpim, P .
TUBERCLE AND LUNG DISEASE, 2000, 80 (02) :69-74
[22]   Polymorphism of variable-number tandem repeats at multiple loci in Mycobacterium tuberculosis [J].
Smittipat, N ;
Billamas, P ;
Palittapongarnpim, M ;
Thong-On, A ;
Temu, MM ;
Thanakijcharoen, P ;
Karnkawinpong, O ;
Palittapongarnpim, P .
JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (10) :5034-5043
[23]   Variable human minisatellite-like regions in the Mycobacterium tuberculosis genome [J].
Supply, P ;
Mazars, E ;
Lesjean, S ;
Vincent, V ;
Gicquel, B ;
Locht, C .
MOLECULAR MICROBIOLOGY, 2000, 36 (03) :762-771
[24]   Identification of novel intergenic repetitive units in a mycobacterial two-component system operon [J].
Supply, P ;
Magdalena, J ;
Himpens, S ;
Locht, C .
MOLECULAR MICROBIOLOGY, 1997, 26 (05) :991-1003
[25]   Automated high-throughput genotyping for study of global epidemiology of Mycobacterium tuberculosis based on mycobacterial interspersed repetitive units [J].
Supply, P ;
Lesjean, S ;
Savine, E ;
Kremer, K ;
van Soolingen, D ;
Locht, C .
JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (10) :3563-3571
[26]   Proposal for standardization of optimized mycobacterial interspersed repetitive unit-variable-number tandem repeat typing of Mycobacterium tuberculosis [J].
Supply, Philip ;
Allix, Caroline ;
Lesjean, Sarah ;
Cardoso-Oelemann, Mara ;
Ruesch-Gerdes, Sabine ;
Willery, Eve ;
Savine, Evgueni ;
de Haas, Petra ;
van Deutekom, Henk ;
Roring, Solvig ;
Bifani, Pablo ;
Kurepina, Natalia ;
Kreiswirth, Barry ;
Sola, Christophe ;
Rastogi, Nalin ;
Vatin, Vincent ;
Gutierrez, Maria Cristina ;
Fauville, Maryse ;
Niemann, Stefan ;
Skuce, Robin ;
Kremer, Kristin ;
Locht, Camille ;
van Soolingen, Dick .
JOURNAL OF CLINICAL MICROBIOLOGY, 2006, 44 (12) :4498-4510
[27]   PREDOMINANCE OF A SINGLE GENOTYPE OF MYCOBACTERIUM-TUBERCULOSIS IN COUNTRIES OF EAST-ASIA [J].
VANSOOLINGEN, D ;
QIAN, LS ;
DEHAAS, PEW ;
DOUGLAS, JT ;
TRAORE, H ;
PORTAELS, F ;
QING, HZ ;
ENKHSAIKAN, D ;
NYMADAWA, P ;
VANEMBDEN, JDA .
JOURNAL OF CLINICAL MICROBIOLOGY, 1995, 33 (12) :3234-3238
[28]   Evaluation of variable numbers of tandem repeat as molecular epidemiological markers of Mycobacterium tuberculosis in Japan [J].
Wada, Takayuki ;
Maeda, Shinji ;
Hase, Atsushi ;
Kobayashi, Kazuo .
JOURNAL OF MEDICAL MICROBIOLOGY, 2007, 56 (08) :1052-1057
[29]   Genotypes and Characteristics of Clustering and Drug Susceptibility of Mycobacterium tuberculosis Isolates Collected in Heilongjiang Province, China [J].
Wang, Juan ;
Liu, Yan ;
Zhang, Chun-Lei ;
Ji, Bin-Ying ;
Zhang, Liu-Zhuo ;
Shao, Yong-Zhen ;
Jiang, Shui-Lian ;
Suzuki, Yasuhiko ;
Nakajima, Chie ;
Fan, Chang-Long ;
Ma, Yuan-Ping ;
Tian, Geng-Wen ;
Hattori, Toshio ;
Ling, Hong .
JOURNAL OF CLINICAL MICROBIOLOGY, 2011, 49 (04) :1354-1362
[30]  
Warren RM., 2003, Am J Respir Crit Care Med
1234