Consumption of sweet beverages and type 2 diabetes incidence in European adults: results from EPIC-InterAct

被引：192

作者：

Romaguera, D. ^{[1
,2
]}

Norat, T. ^{[1
]}

Wark, P. A. ^{[1
]}

Vergnaud, A. C. ^{[1
]}

Schulze, M. B. ^{[3
]}

van Woudenbergh, G. J. ^{[4
]}

Drogan, D. ^{[3
]}

Amiano, P. ^{[5
,6
]}

Molina-Montes, E. ^{[7
,8
]}

Sanchez, M. J. ^{[7
,8
]}

Balkau, B. ^{[9
,10
]}

Barricarte, A. ^{[8
,11
]}

Beulens, J. W. J. ^{[12
]}

Clavel-Chapelon, F. ^{[10
,13
]}

Crispim, S. P. ^{[14
]}

Fagherazzi, G. ^{[10
,13
]}

Franks, P. W. ^{[15
]}

Grote, V. A. ^{[16
]}

Huybrechts, I. ^{[14
]}

Kaaks, R.

Key, T. J. ^{[17
]}

Khaw, K. T. ^{[18
]}

Nilsson, P. ^{[15
]}

Overvad, K. ^{[19
,20
]}

Palli, D. ^{[21
]}

Panico, S. ^{[22
]}

Quiros, J. R.

Rolandsson, O. ^{[23
]}

Sacerdote, C. ^{[24
,25
]}

Sieri, S. ^{[26
]}

Slimani, N. ^{[14
]}

Spijkerman, A. M. W. ^{[27
]}

Tjonneland, A. ^{[28
]}

Tormo, M. J. ^{[8
,29
]}

Tumino, R.

van den Berg, S. W. ^{[30
]}

Wermeling, P. R. ^{[31
]}

Zamora-Ros, R. ^{[32
]}

Feskens, E. J. M. ^{[4
]}

Langenberg, C. ^{[33
]}

Sharp, S. J. ^{[33
]}

Forouhi, N. G. ^{[33
]}

Riboli, E. ^{[1
]}

Wareham, N. J. ^{[33
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Dept Epidemiol & Biostat, Sch Publ Hlth, London W2 1PG, England

[2] CIBER Fisiopatol Obesidad & Nutr CIBEROBN, Madrid, Spain

[3] German Inst HumanNutr Potsdam Rehbruecke, Nuthetal, Germany

[4] Wageningen Univ, NL-6700 AP Wageningen, Netherlands

[5] BIODonostia Res Inst, Publ Hlth Div Gipuzkoa, San Sebastian, Spain

[6] CIBER Epidemiol & Salud Publ CIBERESP, Madrid, Spain

[7] Andalusian Sch Publ Hlth, Granada, Spain

[8] CIBERESP, Madrid, Spain

[9] Ctr Res Epidemiol & Populat Hlth CESP, INSERM, U1018, Villejuif, France

[10] Paris South Univ, Villejuif, France

[11] Navarre Publ Hlth Inst ISPN, Pamplona, Spain

[12] Univ Med Ctr, Utrecht, Netherlands

[13] CESP, INSERM, U1018, Villejuif, France

[14] Int Agcy Res Canc, F-69372 Lyon, France

[15] Lund Univ, Malmo, Sweden

[16] German Canc Res Ctr, Heidelberg, Germany

[17] Univ Oxford, Oxford, England

[18] Univ Cambridge, Dept Publ Hlth & Primary Care, Cambridge, England

[19] Sch Publ Hlth, Aarhus, Denmark

[20] Aarhus Univ Hosp, Aalborg Hosp, Aalborg, Denmark

[21] Canc Res & Prevent Inst ISPO, Florence, Italy

[22] Univ Naples Federico II, Dept Clin & Expt Med, Naples, Italy

[23] Umea Univ, Umea, Sweden

[24] Ctr Canc Prevent CPO Piemonte, Turin, Italy

[25] Human Genet Fdn, Turin, Italy

[26] Fdn IRCCS Ist Nazl Tumori, Epidemiol & Prevent Unit, Milan, Italy

[27] Natl Inst Publ Hlth & Environm RIVM, Bilthoven, Netherlands

[28] Danish Canc Soc, Res Ctr, Copenhagen, Denmark

[29] Murcia Reg Hlth Council, Dept Epidemiol, Murcia, Spain

[30] RIVM, Bilthoven, Netherlands

[31] Univ Med Ctr, Utrecht, Netherlands

[32] Catalan Inst Oncol, Barcelona, Spain

[33] Addenbrookes Hosp, Epidemiol Unit, MRC, Cambridge, England

来源：

DIABETOLOGIA | 2013年 / 56卷 / 07期

基金：

瑞典研究理事会;

关键词：

Artificially sweetened soft drinks; Case-cohort study; Europe; Juices and nectars; Prospective study; Sugar-sweetened soft drinks; Sweet beverages; Type 2 diabetes incidence; METABOLIC SYNDROME; WEIGHT-GAIN; RISK; OBESITY; CANCER; PROJECT; DIETARY; COHORT; PATTERNS; TRIAL;

D O I：

10.1007/s00125-013-2899-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Consumption of sugar-sweetened beverages has been shown, largely in American populations, to increase type 2 diabetes incidence. We aimed to evaluate the association of consumption of sweet beverages (juices and nectars, sugar-sweetened soft drinks and artificially sweetened soft drinks) with type 2 diabetes incidence in European adults. We established a case-cohort study including 12,403 incident type 2 diabetes cases and a stratified subcohort of 16,154 participants selected from eight European cohorts participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. After exclusions, the final sample size included 11,684 incident cases and a subcohort of 15,374 participants. Cox proportional hazards regression models (modified for the case-cohort design) and random-effects meta-analyses were used to estimate the association between sweet beverage consumption (obtained from validated dietary questionnaires) and type 2 diabetes incidence. In adjusted models, one 336 g (12 oz) daily increment in sugar-sweetened and artificially sweetened soft drink consumption was associated with HRs for type 2 diabetes of 1.22 (95% CI 1.09, 1.38) and 1.52 (95% CI 1.26, 1.83), respectively. After further adjustment for energy intake and BMI, the association of sugar-sweetened soft drinks with type 2 diabetes persisted (HR 1.18, 95% CI 1.06, 1.32), but the association of artificially sweetened soft drinks became statistically not significant (HR 1.11, 95% CI 0.95, 1.31). Juice and nectar consumption was not associated with type 2 diabetes incidence. This study corroborates the association between increased incidence of type 2 diabetes and high consumption of sugar-sweetened soft drinks in European adults.

引用

页码：1520 / 1530

页数：11

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