Production and Characterization of a Bone-Like Porous Ti/Ti-Hydroxyapatite Functionally Graded Material

被引:62
作者
Yilmaz, Eren [1 ,2 ]
Kabatas, Feyza [3 ]
Gokce, Azim [3 ,4 ]
Findik, Fehim [3 ]
机构
[1] Sakarya Appl Sci Univ, Arifiye Vocat High Sch, Dept Welding Technol, TR-54187 Sakarya, Turkey
[2] Sakarya Appl Sci Univ, Mat Res Ctr SUMAR, TR-54187 Sakarya, Turkey
[3] Sakarya Appl Sci Univ, Fac Technol, Dept Met & Mat Engn, TR-54187 Sakarya, Turkey
[4] Univ Louisville, Mat Innovat Guild, Louisville, KY 40208 USA
关键词
functionally graded materials; implants; porous titanium; hydroxyapatite; powder metallurgy; POWDER-METALLURGY; IN-VITRO; TITANIUM; COATINGS; MICROSTRUCTURE; TEMPERATURE; BIOACTIVITY; COMPOSITE; ALLOY;
D O I
10.1007/s11665-020-05165-2
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
A new kind of functionally graded material (FGM) that mimics the inner porous structure and outer dense layer of human bone was produced using powder metallurgy. The inner part of the FGM material (16 mm in diameter) has porosity of approximately 60%, and its mechanical properties are compatible with cortical bone; however, the shell (1.8 mm in thickness) is composed of a layer of Ti-10% wt. hydroxyapatite (HA) and shows hydrophilic behavior and improved biofunction. Elastic moduli of the core and shell layer were calculated as 18.99 and 42.98 GPa, respectively, and those values are compatible with that of cortical bone. Addition of HA to the shell had a significant effect on the wettability (81.6% decrease) and cell viability (46% increase). Furthermore, the porosity of the shell layer (28.88%) is similar to that of human cortical bone. It is concluded that the developed Ti-HA FGM has promising properties for implant applications.
引用
收藏
页码:6455 / 6467
页数:13
相关论文
共 51 条
[1]   Electrochemical corrosion and bioactivity of titanium-hydroxyapatite composites prepared by spark plasma sintering [J].
Anawati ;
Tanigawa, Hiroaki ;
Asoh, Hidetaka ;
Ohno, Takuya ;
Kubota, Masahiro ;
Ono, Sachiko .
CORROSION SCIENCE, 2013, 70 :212-220
[2]  
Anil S., 2011, Dental Implant Surface Enhancement and Osseointegration, Implant Dentistry - A Rapidly Evolving Practice, DOI DOI 10.5772/16475
[3]   Preparation and characterisation of sol-gel-derived hydroxyapatite nanoparticles and its coatings on medical grade Ti-6Al-4V alloy for biomedical applications [J].
Anjaneyulu, U. ;
Priyadarshini, B. ;
Stango, S. Arul Xavier ;
Chellappa, M. ;
Geetha, M. ;
Vijayalakshmi, U. .
MATERIALS TECHNOLOGY, 2017, 32 (13) :800-814
[4]  
[Anonymous], 2007, Molecular Biology of the Cell
[5]   Material processing of hydroxyapatite and titanium alloy (HA/Ti) composite as implant materials using powder metallurgy: A review [J].
Arifin, Amir ;
Sulong, Abu Bakar ;
Muhamad, Norhamidi ;
Syarif, Junaidi ;
Ramli, Mohd Ikram .
MATERIALS & DESIGN, 2014, 55 :165-175
[6]   Microstructure Development on Sintered Ti/HA Biocomposites Produced by Powder Metallurgy [J].
Balbinotti, Pedro ;
Gemelli, Enori ;
Buerger, Gabriel ;
de Lima, Sarah Amin ;
de Jesus, Jailson ;
Almeida Camargo, Nelson Heriberto ;
Rodrigues Henriques, Vinicius Andre ;
de Almeida Soares, Gloria Dulce .
MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS, 2011, 14 (03) :384-393
[7]   Influence of deposition temperature on the properties of hydroxyapatite obtained by electrochemical assisted deposition [J].
Cotrut, Cosmin M. ;
Vladescu, Alina ;
Dinu, Mihaela ;
Vranceanu, Diana M. .
CERAMICS INTERNATIONAL, 2018, 44 (01) :669-677
[8]   Highly porous titanium scaffolds for orthopaedic applications [J].
Dabrowski, Bogdan ;
Swieszkowski, Wojciech ;
Godlinski, Dirk ;
Kurzydlowski, Krzysztof J. .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2010, 95B (01) :53-61
[9]   Effect of hydroxyapatite particle size, morphology and crystallinity on proliferation of colon cancer HCT116 cells [J].
Dey, Sangeeta ;
Das, Mitun ;
Balla, Vamsi Krishna .
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2014, 39 :336-339
[10]   Plasma-Sprayed Hydroxyapatite Coating for Improved Corrosion Resistance and Bioactivity of Magnesium Alloy [J].
Gao, Ya Li ;
Liu, Yu ;
Song, Xue Ying .
JOURNAL OF THERMAL SPRAY TECHNOLOGY, 2018, 27 (08) :1381-1387