Phylogenetic analysis and circulation pattern of human metapneumovirus strains in children with acute respiratory infection in Iran, 2014-2015

被引：1
作者：
Babaei, Abouzar [1 ]
Malekshahi, Somayeh Shatizadeh [2 ]
Pirbonyeh, Neda [1 ]
Sarvari, Jamal [1 ]
Moattari, Afagh [1 ]
机构：
[1] Shiraz Univ Med Sci, Dept Bacteriol & Virol, Shiraz, Iran
[2] Tarbiat Modares Univ, Dept Virol, Fac Med Sci, Tehran, Iran
来源：
FUTURE VIROLOGY | 2020年 / 15卷 / 07期
关键词：
acute respiratory infection; epidemiology; human metapneumovirus; Iran; phylogenetic analysis; TRACT INFECTIONS; GENETIC DIVERSITY; SYNCYTIAL VIRUS; HOSPITALIZED CHILDREN; HUMAN BOCAVIRUS; YOUNG-CHILDREN; PREVALENCE; DISEASE; VARIABILITY; SEVERITY;
D O I：
10.2217/fvl-2020-0013
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Aim:The aim of the present study was to investigate the prevalence and genetic variation of the human metapneumovirus (HMPV)Ggene in children less than 8 years old with acute respiratory tract infections in Iran during 2014-2015.Materials & methods:To this end, 110 nasal swabs were tested for HMPVFgene. All positive samples were tested for the full length of HMPVGgene, then sequenced and analyzed for phylogenetic grouping.Results:Six (5.45%) out of 110 samples were positive for HMPV gene. Our HMPV sequences clustered into two main clusters: A2b (five isolates) and B1 (one isolate). The dN/dS ratio showed the presence of negative selective pressure.Conclusion:A2b was the predominant genotype during the study period in southwest of Iran.
引用
收藏
页码：419 / 427
页数：9
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