Fire-diffuse-fire model of dynamics of intracellular calcium waves

被引：139

作者：

Dawson, SP

Keizer, J

Pearson, JE ^{[1
]}

机构：

[1] Univ Calif Davis, Inst Theoret Dynam & Neurobiol Physiol & Behav, Davis, CA 95616 USA

[2] Univ Calif Los Alamos Natl Lab, Div Appl Theoret Phys, Los Alamos, NM 87545 USA

[3] Univ Buenos Aires, Fac Ciencias Exactas & Nat, Dept Fis, RA-1428 Buenos Aires, DF, Argentina

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1999年 / 96卷 / 11期

关键词：

D O I：

10.1073/pnas.96.11.6060

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

When Ca2+ is released from internal stores in living cells, the resulting wave of increased concentration can travel without deformation (continuous propagation) or with burst-like behavior (saltatory propagation). We analyze the "fire-diffuse-fire'' model in order to illuminate the differences between these two modes of propagation. We show that the Ca2+ release wave in immature Xenopus oocytes and cardiac myocytes is saltatory, whereas the fertilization wave in the mature oocyte is continuous.

引用

页码：6060 / 6063

页数：4

共 28 条

[1] RANGE OF MESSENGER ACTION OF CALCIUM-ION AND INOSITOL 1,4,5-TRISPHOSPHATE [J].