Comprehensive assay of flavanones in citrus juices and beverages by UHPLC-ESI-MS/MS and derivatization chemistry

被引：45
作者：
Di Donna, Leonardo [1 ]
Taverna, Domenico [1 ]
Mazzotti, Fabio [1 ]
Benabdelkamel, Hicham [1 ,2 ]
Attya, Mohamed [1 ,3 ]
Napoli, Anna [1 ]
Sindona, Giovanni [1 ]
机构：
[1] Univ Calabria, Dipartimento Chim, I-87036 Cosenza, Italy
[2] King Saud Univ, Obes Res Ctr, Coll Med, Riyadh 11451, Saudi Arabia
[3] King Saud Univ, King Khalid Univ Hosp, Clin Biochem Lab, Riyadh 11451, Saudi Arabia
来源：
FOOD CHEMISTRY | 2013年 / 141卷 / 03期
关键词：
Flavonoids assay; Brutieridin; Derivatization chemistry; Multiple reaction monitoring (MRM); Isotope dilution; TANDEM MASS-SPECTROMETRY; ELECTROSPRAY-IONIZATION; LIQUID-CHROMATOGRAPHY; ISOTOPE-DILUTION; FLAVONOIDS; METABOLISM; PRINCIPLES; LEAVES; FOOD; OIL;
D O I：
10.1016/j.foodchem.2013.05.034
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Flavanones, a class of flavonoids present in large amounts in fruits and vegetables, have been assayed by LC-MS/MS and derivatization chemistry using d(0)/d(3)-labelled derivatized internal standards obtained by simple reaction procedures which involves d(0)/d(3) methoxyamine. The assay method considers 13 flavanones including aglycones, neohesperidosides, rutinosides and 3-hydroxy-3-methyl glutaryl derivatives. The strengths of the method consist in a relative short analysis time (16 min) and good repeatability and reproducibility values which are in most cases under 10% (RSD%). The accuracy values range from 95.4% to 111.3% whilst the LOQ values ranges from 0.05 to 0.29 mg/L depending on the analyte. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2328 / 2333
页数：6
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