Use of semiflexible applicators for radiofrequency ablation of liver tumors

被引:12
作者
Gaffke, G
Gebauer, B
Knollmann, FD
Helmberger, T
Ricke, J
Oettle, H
Felix, R
Stroszczynski, C
机构
[1] Univ Med Berlin, Klin Strahlenheilkunde & Poliklin, Charite, D-13353 Berlin, Germany
[2] Univ Munich, Inst Klin Radiol Grosshadern, D-81377 Munich, Germany
[3] Univ Med Berlin, Med Klin Schwerpunkt Hamatol & Onkol, Charite, D-13353 Berlin, Germany
关键词
intervention; liver; metastasis; MRI; radiofrequency ablation;
D O I
10.1007/s00270-005-0052-x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose: To evaluate the feasibility and potential advantages of the radiofrequency ablation of liver tumors using new MRI-compatible semiflexible applicators in a closed-bore high-field MRI scanner. Methods: We treated 8 patients with 12 malignant liver tumors of different origin (5 colorectal carcinoma, 2 cholangiocellular carcinoma, 1 breast cancer) under MRI guidance. Radiofrequency ablation (RFA) was performed using 5 cm Rita Starburst Semi-Flex applicators (Rita Medical Systems, Milwaukee, WI, USA) which are suitable for MR- and CT-guided interventions and a 150 W RF generator. All interventions were performed in a closed-bore 1.5 T high-field MRI scanner for MRI-guided RFA using fast T1-weighted gradient echo sequences and T2-weighted ultra-turbo spin echo sequences. Control and follow-up MRI examinations were performed on the next day, at 6 weeks, and every 3 months after RFA. Control MRI were performed as double-contrast MRI examinations (enhancement with iron oxide and gadopentetate dimeglumine). All interventions were performed with the patient under local anesthesia and analgo-sedation. Results: The mean diameter of the treated hepatic tumors was 2.4 cm (+/- 0.6 cm, range 1.0-3.2 cm). The mean diameter of induced necrosis was 3.1 cm (+/- 0.4 cm). We achieved complete ablation in all patients. Follow-up examinations over a duration of 7 months (+/- 1.3 months, range 4-9 month) showed a local control rate of 100% in this group of patients. All interventions were performed without major complications; only 2 subcapsular hematomas were documented. Conclusions: RFA of liver tumors using semiflexible applicators in closed-bore 1.5 T scanner systems is feasible. These applicators might simplify the RFA of liver tumors under MRI control. The stiff distal part of the applicator facilitates its repositioning.
引用
收藏
页码:270 / 275
页数:6
相关论文
共 30 条
[1]  
FAFFKE G, 2005, ROFO FORTSCHR RONTG, V177, P77
[2]   Radiofrequency ablation of cancer [J].
Friedman, M ;
Mikityansky, I ;
Kam, A ;
Libutti, SK ;
Walther, MM ;
Neeman, Z ;
Locklin, JK ;
Wood, BJ .
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 2004, 27 (05) :427-434
[3]  
Gebauer B, 2003, ROFO-FORTSCHR RONTG, V175, P1720
[4]   Survival after percutaneous, image-guided, thermal ablation of hepatic metastases from colorectal cancer [J].
Gillams, AR ;
Lees, WR .
DISEASES OF THE COLON & RECTUM, 2000, 43 (05) :656-661
[5]   Comparing the outcomes of radiofrequency ablation and surgery in patients with a single small hepatocellular carcinoma and well-preserved hepatic function [J].
Hong, SN ;
Lee, SY ;
Choi, MS ;
Lee, JH ;
Koh, KC ;
Paik, SW ;
Yoo, BC ;
Rhee, JC ;
Choi, D ;
Lim, HK ;
Lee, KW ;
Joh, JW .
JOURNAL OF CLINICAL GASTROENTEROLOGY, 2005, 39 (03) :247-252
[6]   MR-guided radiofrequency ablation of hepatic neoplasms [J].
Huppert, PE ;
Trübenbach, J ;
Schick, F ;
Pereira, P ;
König, C ;
Claussen, CD .
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN, 2000, 172 (08) :692-700
[7]   Laserinduced thermotherapy (LITT) of experimental livermetastasis -: Detection of residual tumors using Gd-DTPA enhanced MRI [J].
Isbert, C ;
Ritz, JP ;
Schilling, A ;
Roggan, A ;
Heiniche, A ;
Wolf, KJ ;
Müller, G ;
Buhr, HJ ;
Germer, CT .
LASERS IN SURGERY AND MEDICINE, 2002, 30 (04) :280-289
[8]   The impact of the perception of treatment choice on satisfaction with treatment, experienced chemotherapy burden and current quality of life [J].
Jansen, SJT ;
Otten, W ;
van de Velde, CJH ;
Nortier, JWR ;
Stiggelbout, AM .
BRITISH JOURNAL OF CANCER, 2004, 91 (01) :56-61
[9]   Percutaneous treatment of liver tumors with an adapted probe for cooled-tip, impedance-controlled radio-frequency ablation under open-magnet MR guidance: initial results [J].
Kelekis, AD ;
Terraz, S ;
Roggan, A ;
Terrier, FO ;
Majno, P ;
Mentha, G ;
Roth, A ;
Becker, CD .
EUROPEAN RADIOLOGY, 2003, 13 (05) :1100-1105
[10]   Percutaneous saline-enhanced radiofrequency ablation of unresectable hepatic tumors:: Initial experience in 26 patients [J].
Kettenbach, J ;
Köstler, W ;
Rücklinger, E ;
Gustorff, B ;
Hüpfl, M ;
Wolf, F ;
Peer, K ;
Weigner, M ;
Lammer, J ;
Müller, W ;
Goldberg, SN .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2003, 180 (06) :1537-1545