Psychogenic nonepileptic seizures: A current overview

被引:64
作者
Dickinson, Philip [1 ]
Looper, Karl J. [2 ,3 ]
机构
[1] McGill Univ, Fac Med, Dept Neurol & Neurosurg, Montreal, PQ, Canada
[2] McGill Univ, Dept Psychiat, Montreal, PQ, Canada
[3] McGill Univ, Jewish Gen Hosp, Dept Psychiat, Montreal, PQ H3T 1E2, Canada
关键词
Functional neurological disorders; Qualitative research; Communication; Functional magnetic resonance imaging; Resting state; SEXUAL-ABUSE; FUNCTIONAL CONNECTIVITY; CONVERSION DISORDER; HIPPOCAMPAL VOLUME; CLINICAL-FEATURES; CLUSTER-ANALYSIS; DEFAULT-MODE; DIAGNOSIS; EPILEPSY; PSEUDOSEIZURES;
D O I
10.1111/j.1528-1167.2012.03606.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Psychogenic nonepileptic seizures (PNES) resemble epilepsy, but no pathophysiological explanation has been established. Although there have been recent advances in PNES research and various hypotheses as to the psychopathology, no theory has achieved general acceptance. In this overview of selected literature on PNES, we highlight the often contradictory findings that underline the challenges that confront both practitioner and researcher. We first provide a synopsis of the history, diagnosis, treatment, and outcomes, as well as patient characteristics of PNES and the relevance of communication in the clinical context. In the subsequent sections we discuss recent research that may advance the understanding and diagnosis of this disorder. These themes include the use of qualitative methods as a viable research option, the application of nonlinear methods to analyze heterogeneous observations during diagnosis, recent advances in neuroimaging of PNES, and the development of international databases.
引用
收藏
页码:1679 / 1689
页数:11
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