Nitriles in organic synthesis: A convenient route to some heterocycles incorporating a benzothiazole moiety

被引：16
作者：
Zaki, M. E. A.
Fadda, A. A. [1 ]
Samir, K.
Amer, F. A.
机构：
[1] Mansoura Univ, Fac Sci, Dept Chem, Mansoura, Egypt
[2] Natl Res Ctr, Photochem Dept, Cairo, Egypt
来源：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2006年 / 181卷 / 08期
关键词：
benzothiazole; chloroactyl chloride; 2-cyanomethylbenzothiazole;
D O I：
10.1080/10426500500542828
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
2-(Benzo[d]thiazol-2-yl)-4-chloro-3-oxobutanenitrile (2) was utilized for the synthesis of several new benzothiazole derivatives. Compound 2 reacted with aniline, hydrazine hydrate, ethanolamine, and ethyl glycinate hydrochloride to yield benzothiazole derivatives 3-6, respectively.
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页码：1815 / 1823
页数：9
相关论文
共 26 条
[1]  
Ahluwalia VK, 1997, INDIAN J CHEM B, V36, P920
[2]  
Brown H.D., 1966, U.S. Patent, Patent No. [3278547, 3,278,547]
[3]  
El-Sherbeny MA, 2000, ARZNEIMITTELFORSCH, V50, P848
[4]  
ELSHAFEI AK, 1987, GAZZ CHIM ITAL, V117, P385
[5]   Revised synthesis of some new 2-heterocyclic benzothiazolyl derivatives of biological interest [J].
Fadda, AA ;
Amer, FA ;
Zaki, MEA ;
Samir, KH .
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 1999, 155 :59-66
[6]  
GEWALD K, 1989, Patent No. 273441
[7]  
GHONEIM KM, 1991, REV ROUM CHIM, V36, P1355
[8]  
GOTO T, 1999, Patent No. 1180155
[9]  
HIROMI OH, 1993, Patent No. 0559003
[10]  
Ilford, 1961, British Patent, Patent No. 867592
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