Geographical Distribution of Genetic Variants and Lineages of SARS-CoV-2 in Chile

被引：20

作者：

Castillo, Andres E. ^{[1
]}

Parra, Barbara ^{[1
]}

Tapia, Paz ^{[1
]}

Lagos, Jaime ^{[1
]}

Arata, Loredana ^{[1
]}

Acevedo, Alejandra ^{[2
]}

Andrade, Winston ^{[2
]}

Leal, Gabriel ^{[2
]}

Tambley, Carolina ^{[2
]}

Bustos, Patricia ^{[2
]}

Fasce, Rodrigo ^{[2
]}

Fernandez, Jorge ^{[1
]}

机构：

[1] Inst Publ Hlth Chile, Mol Genet Sub Dept, Santiago, Chile

[2] Inst Publ Hlth Chile, Sect Resp & Exanthemat Viruses, Santiago, Chile

来源：

FRONTIERS IN PUBLIC HEALTH | 2020年 / 8卷

关键词：

COVID-19; SARS-CoV; 2; epidemiology; variants; lineages;

D O I：

10.3389/fpubh.2020.562615

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The pandemic caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a worldwide public health concern. First confined in China and then disseminated widely across Europe and America, SARS-CoV-2 has impacted and moved the scientific community around the world to working in a fast and coordinated way to collect all possible information about this virus and generate new strategies and protocols to try to stop the infection. During March 2020, more than 16,000 full viral genomes have been shared in public databases that allow the construction of genetic landscapes for tracking and monitoring the viral advances over time and study the genomic variations present in geographic regions. In this work, we present the occurrence of genetic variants and lineages of SARS-CoV-2 in Chile during March to April 2020. Complete genome analysis of 141 viral samples from different regions of Chile revealed a predominance of variant D614G like in Europe and the USA and the major presence of lineage B.1. These findings could help take control measures due to the similarity of the viral variants present in Chile, compared with other countries, and monitor the dynamic change of virus variants in the country.

引用

页数：7

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