Direct addition of TMS-acetylene to aldimines catalyzed by a simple, commercially available Ir(I) complex

被引：259

作者：

Fischer, C ^{[1
]}

Carreira, EM ^{[1
]}

机构：

[1] ETH Honggerberg, Organ Chem Lab, CH-8093 Zurich, Switzerland

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 26期

关键词：

D O I：

10.1021/ol017022q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A new, convenient procedure for the addition reaction of trimethylsilylacetylene to imines is described. Simply treating a solution of aldimine and trimethylsilyl acetylene with catalytic [IrCl(COD)](2) furnishes the adduct in preparatively useful yields. Interestingly, the reaction may be conducted in the absence of solvent.

引用

页码：4319 / 4321

页数：3

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