Klotho A Master Regulator of Cardiovascular Disease?

被引:48
作者
Moe, Sharon M. [1 ,2 ]
机构
[1] Indiana Univ Sch Med, Indianapolis, IN 46202 USA
[2] Roudebush Vet Adm, Med Ctr, Indianapolis, IN USA
关键词
Editorials; kidney; renal; vascular calcification; vascular disease; FGF-23; phosphorus; KIDNEY-DISEASE; VITAMIN-D; PHOSPHATE; MOUSE; GENE; EXPRESSION; RECEPTOR; HEART;
D O I
10.1161/CIRCULATIONAHA.112.104828
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:2181 / 2183
页数:3
相关论文
共 24 条
[1]   The relationship between the soluble Klotho protein and the residual renal function among peritoneal dialysis patients [J].
Akimoto, Tetsu ;
Shiizaki, Kazuhiro ;
Sugase, Taro ;
Watanabe, Yuko ;
Yoshizawa, Hiromichi ;
Otani, Naoko ;
Numata, Akihiko ;
Takeshima, Eri ;
Yamazaki, Tomoyuki ;
Miki, Takuya ;
Ito, Chiharu ;
Pastor, Johanne V. ;
Iwazu, Yoshitaka ;
Saito, Osamu ;
Muto, Shigeaki ;
Kuro-o, Makoto ;
Kusano, Eiji .
CLINICAL AND EXPERIMENTAL NEPHROLOGY, 2012, 16 (03) :442-447
[2]   Validation of an Immunoassay for Soluble Klotho Protein Decreased Levels in Diabetes and Increased Levels in Chronic Kidney Disease [J].
Devaraj, Sridevi ;
Syed, Basir ;
Chien, Alexander ;
Jialal, Ishwarlal .
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2012, 137 (03) :479-485
[3]   Relations of serum phosphorus and calcium levels to the incidence of cardiovascular disease in the community [J].
Dhingra, Ravi ;
Sullivan, Lisa M. ;
Fox, Caroline S. ;
Wang, Thomas J. ;
D'Agostino, Ralph B. ;
Gaziano, J. Michael ;
Vasan, Ramachandran S. .
ARCHIVES OF INTERNAL MEDICINE, 2007, 167 (09) :879-885
[4]   FGF23 induces left ventricular hypertrophy [J].
Faul, Christian ;
Amaral, Ansel P. ;
Oskouei, Behzad ;
Hu, Ming-Chang ;
Sloan, Alexis ;
Isakova, Tamara ;
Gutierrez, Orlando M. ;
Aguillon-Prada, Robier ;
Lincoln, Joy ;
Hare, Joshua M. ;
Mundel, Peter ;
Morales, Azorides ;
Scialla, Julia ;
Fischer, Michael ;
Soliman, Elsayed Z. ;
Chen, Jing ;
Go, Alan S. ;
Rosas, Sylvia E. ;
Nessel, Lisa ;
Townsend, Raymond R. ;
Feldman, Harold I. ;
Sutton, Martin St. John ;
Ojo, Akinlolu ;
Gadegbeku, Crystal ;
Di Marco, Giovana Seno ;
Reuter, Stefan ;
Kentrup, Dominik ;
Tiemann, Klaus ;
Brand, Marcus ;
Hill, Joseph A. ;
Moe, Orson W. ;
Kuro-o, Makoto ;
Kusek, John W. ;
Keane, Martin G. ;
Wolf, Myles .
JOURNAL OF CLINICAL INVESTIGATION, 2011, 121 (11) :4393-4408
[5]   Vitamin D receptor controls expression of the anti-aging klotho gene in mouse and human renal cells [J].
Forster, Ryan E. ;
Jurutka, Peter W. ;
Hsieh, Jui-Cheng ;
Haussler, Carol A. ;
Lowmiller, Christine L. ;
Kaneko, Ichiro ;
Haussler, Mark R. ;
Whitfield, G. Kerr .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2011, 414 (03) :557-562
[6]   Klotho Deficiency Causes Vascular Calcification in Chronic Kidney Disease [J].
Hu, Ming Chang ;
Shi, Mingjun ;
Zhang, Jianning ;
Quinones, Henry ;
Griffith, Carolyn ;
Kuro-o, Makoto ;
Moe, Orson W. .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2011, 22 (01) :124-136
[7]   Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule [J].
Hu, Ming Chang ;
Shi, Mingjun ;
Zhang, Jianning ;
Pastor, Johanne ;
Nakatani, Teruyo ;
Lanske, Beate ;
Razzaque, M. Shawkat ;
Rosenblatt, Kevin P. ;
Baum, Michel G. ;
Kuro-o, Makoto ;
Moe, Orson W. .
FASEB JOURNAL, 2010, 24 (09) :3438-3450
[8]   Fibroblast Growth Factor 23 and Risks of Mortality and End-Stage Renal Disease in Patients With Chronic Kidney Disease [J].
Isakova, Tamara ;
Xie, Huiliang ;
Yang, Wei ;
Xie, Dawei ;
Anderson, Amanda Hyre ;
Scialla, Julia ;
Wahl, Patricia ;
Gutierrez, Orlando M. ;
Steigerwalt, Susan ;
He, Jiang ;
Schwartz, Stanley ;
Lo, Joan ;
Ojo, Akinlolu ;
Sondheimer, James ;
Hsu, Chi-yuan ;
Lash, James ;
Leonard, Mary ;
Kusek, John W. ;
Feldman, Harold I. ;
Wolf, Myles .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2011, 305 (23) :2432-2439
[9]   Fibroblast growth factor-23 and early decrements in kidney function: the Heart and Soul Study [J].
Ix, Joachim H. ;
Shlipak, Michael G. ;
Wassel, Christina L. ;
Whooley, Mary A. .
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2010, 25 (03) :993-997
[10]   Severely reduced production of Klotho in human chronic renal failure kidney [J].
Koh, N ;
Fujimori, T ;
Nishiguchi, S ;
Tamori, A ;
Shiomi, S ;
Nakatani, T ;
Sugimura, K ;
Kishimoto, T ;
Kinoshita, S ;
Kuroki, T ;
Nabeshima, Y .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2001, 280 (04) :1015-1020