HIV-1 entry inhibitors in the side pocket

被引：84

作者：

Sodroski, JG ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Dept Canc Immunol & AIDS, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Dana Farber Canc Inst, Boston, MA 02115 USA

[3] Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA

[4] Harvard Univ, Sch Publ Hlth, Dept Immunol & Infect Dis, Boston, MA 02115 USA

来源：

CELL | 1999年 / 99卷 / 03期

关键词：

D O I：

10.1016/S0092-8674(00)81655-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：243 / 246

页数：4

共 18 条

[1] EFFECTS OF AMINO-ACID CHANGES IN THE EXTRACELLULAR DOMAIN OF THE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 GP41 ENVELOPE GLYCOPROTEIN [J].

CAO, J ;

BERGERON, L ;

HELSETH, E ;

THALI, M ;

REPKE, H ;

SODROSKI, J .

JOURNAL OF VIROLOGY, 1993, 67 (05) :2747-2755

[2] Core structure of gp41 from the HIV envelope glycoprotein [J].

Chan, DC ;

Fass, D ;

Berger, JM ;

Kim, PS .

CELL, 1997, 89 (02) :263-273

[3] Evidence that a prominent cavity in the coiled coil of HIV type 1 gp41 is an attractive drug target [J].

Chan, DC ;

Chutkowski, CT ;

Kim, PS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (26) :15613-15617

[4] HIV entry and its inhibition [J].

Chan, DC ;

Kim, PS .

CELL, 1998, 93 (05) :681-684

[5] MUTATIONS IN THE LEUCINE ZIPPER OF THE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 TRANSMEMBRANE GLYCOPROTEIN AFFECT FUSION AND INFECTIVITY [J].

DUBAY, JW ;

ROBERTS, SJ ;

BRODY, B ;

HUNTER, E .

JOURNAL OF VIROLOGY, 1992, 66 (08) :4748-4756

[6] Inhibiting HIV-1 entry: Discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket [J].

Eckert, DM ;

Malashkevich, VN ;

Hong, LH ;

Carr, PA ;

Kim, PS .

CELL, 1999, 99 (01) :103-115

[7]

Ferrer M, 1999, NAT STRUCT BIOL, V6, P953

[8] Capture of an early fusion-active conformation of HIV-1 gp41 [J].

Furuta, RA ;

Wild, CT ;

Weng, YK ;

Weiss, CD .

NATURE STRUCTURAL BIOLOGY, 1998, 5 (04) :276-279

[9] HIV-1 INHIBITION BY A PEPTIDE [J].

JIANG, SB ;

LIN, K ;

STRICK, N ;

NEURATH, AR .

NATURE, 1993, 365 (6442) :113-113

[10] Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry [J].

Kilby, JM ;

Hopkins, S ;

Venetta, TM ;

DiMassimo, B ;

Cloud, GA ;

Lee, JY ;

Alldredge, L ;

Hunter, E ;

Lambert, D ;

Bolognesi, D ;

Mathews, T ;

Johnson, MR ;

Nowak, MA ;

Shaw, GM ;

Saag, MS .

NATURE MEDICINE, 1998, 4 (11) :1302-1307

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