Sarcoidosis associated with neuromyelitis optica

被引：24

作者：

Sawaya, Raja ^{[1
]}

Radwan, Wael ^{[1
]}

机构：

[1] Amer Univ Med Ctr, Dept Internal Med, Div Neurol, Beirut 11072020, Lebanon

来源：

JOURNAL OF CLINICAL NEUROSCIENCE | 2013年 / 20卷 / 08期

关键词：

Anti-aquaporin; 4; Autoimmune diseases; Neuromyelitis optica; Rituximab; Sarcoidosis;

D O I：

10.1016/j.jocn.2012.09.030

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Neuromyelitis optica (NMO) is an autoimmune disorder diagnosed by an elongated spinal cord lesion associated with unilateral or bilateral optic neuritis and anti-aquaporin 4 (AQP4) antibodies in the serum. It is triggered by or associated with several autoimmune diseases, but not with sarcoidosis. It responds to immunomodulators better than to steroid treatment. Sarcoidosis is an autoimmune disorder which manifests as non-caseating granulomas, usually in the lung parenchyma, but also in other tissues, including the brain. The involvement of the central nervous system in neurosarcoidosis differs considerably from that in neuromyelitis optica and the association of these two diseases concurrently in the same patient is unusual. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：1156 / 1158

页数：3

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