A highly regioselective synthesis of 2-aryl-6-chlorobenzothiazoles employing microwave-promoted Suzuki-Miyaura coupling reaction

被引：60
|
作者：
Heo, Y [1 ]
Song, YS [1 ]
Kim, BT [1 ]
Heo, JN [1 ]
机构：
[1] Korea Res Inst Chem Technol, Bioorgan Sci Div, Taejon 305600, South Korea
来源：
TETRAHEDRON LETTERS | 2006年 / 47卷 / 18期
关键词：
Suzuki-Miyaura reaction; palladium; boronic acid; microwave; benzothiazole; amination;
D O I：
10.1016/j.tetlet.2006.02.152
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Suzuki-Miyaura coupling reactions of 2,6-dichlorobenzothiazole with arylboronic acids, promoted by microwave heating, efficiently produce 2-aryl-6-chlorobenzothiazoles in a highly regioselective manner. This process serves as the foundation for a simple method to rapidly construct 2-aryl-6-chlorobenzothiazole libraries. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：3091 / 3094
页数：4
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