Role of miR-155 in breast cancer

被引：27

作者：

Wang, Jie ^{[1
]}

Wu, Jianhua ^{[1
]}

机构：

[1] Fudan Univ, Hushan Hosp, Dept Surg, Shanghai 200040, Peoples R China

来源：

FRONTIERS IN BIOSCIENCE-LANDMARK | 2012年 / 17卷

关键词：

Acute lung injury; Acute respiratory distress syndrome; Polymorphonuclear neutrophil; Review; TRANSCRIPTION FACTOR FOXO3A; CELL-SURVIVAL; TGF-BETA; EXPRESSION; MICRORNAS; GROWTH; RNA; MODULATION; POLARITY; PATHWAY;

D O I：

10.2741/4056

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Breast cancer is the second leading cause of death due to cancer in women. Accumulating evidence shows a correlation between overexpression of miR-155 and breast cancer development. The microRNA (miRNA) encoded by mir-155 is known to be oncogenic in multiple tumors. This review summarizes the signaling pathways that are regulated by miR-155 in breast cancer and discusses therapeutic possibilities related to miR-155.

引用

页码：2350 / 2355

页数：6

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