Developmental expression of cardiac myosin-binding protein C in Xenopus

被引：1
作者：
Duan, LJ
George, ME
Drysdale, TA
机构：
[1] Univ Western Ontario, Lawson Hlth Res Inst, Dept Paediat, London, ON N6A 4V2, Canada
[2] Univ Western Ontario, Lawson Hlth Res Inst, Dept Physiol, London, ON N6A 4V2, Canada
[3] Univ Western Ontario, Lawson Hlth Res Inst, Dept Zool, London, ON N6A 4V2, Canada
来源：
DEVELOPMENT GENES AND EVOLUTION | 2002年 / 212卷 / 01期
基金：
加拿大健康研究院;
关键词：
heart; myocardium; somite; Xenopus; cardiogenesis;
D O I：
10.1007/s00427-001-0199-7
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
We have isolated the Xenopus homologue of cardiac myosin-binding protein C (cMyBP-C) and describe its expression during early embryogenesis. cMyBP-C is expressed in both somites and heart at the time these tissues differentiate. Expression in the somites declines in older tadpoles. There is a high degree of conservation in residues where mutations causing hypertrophic cardiomyopathy have been identified in humans.
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页码：47 / 49
页数：3
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