Epicardial ablation of ventricular tachycardia: An institutional experience of safety and efficacy

被引:98
作者
Tung, Roderick [1 ]
Michowitz, Yoav [1 ]
Yu, Ricky [1 ]
Mathuria, Nilesh [1 ]
Vaseghi, Marmar [1 ]
Buch, Eric [1 ]
Bradfield, Jason [1 ]
Fujimura, Osamu [1 ]
Gima, Jean [1 ]
Discepolo, William [1 ]
Mandapati, Ravi [1 ]
Boyle, Noel [1 ]
Shivkumar, Kalyanam [1 ]
机构
[1] Univ Calif Los Angeles, UCLA Cardiac Arrhythmia Ctr, UCLA Hlth Syst, David Geffen Sch Med, Los Angeles, CA 90095 USA
关键词
Ventricular tachycardia; Ablation; Epicardial; RADIOFREQUENCY CATHETER ABLATION; SUBSTRATE; ARRHYTHMIAS; SCAR;
D O I
10.1016/j.hrthm.2012.12.013
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND Epicardial ablation has been shown to be a useful adjunct for treatment of ventricular tachycardia (VT). OBJECTIVE To report the trends, safety, and efficacy of epicardial mapping and ablation at a singe center over an 8-year period. METHODS Patients referred for VT ablation (June 2004 to Jury 2011) were divided into 3 groups: ischemic cardiomyopathy (ICM), nonischemic cardiomyopathy (NICM), and idiopathic ventricular arrhythmias (VA). Patients with scar-mediated VT who underwent combined epicardial and endocardial (epi-endo) mapping and ablation were compared with those who underwent endocardial-only (endo-only) ablation with regard to patient characteristics, acute procedural success, 6- and 12-month clinical outcomes. RESULTS Among 144 patients referred for VT ablation, 95 patients underwent 109 epicardial procedures (94% access rate). Major complications were seen in 8 patients (8.8%) with pericardial breeding (>80 cm(3)) in 6 cases (6.7%), although no tamponade, surgical intervention, or procedural mortality was seen. Patients with ICM who underwent a combined epi-endo ablation had improved freedom from VT compared with those who underwent endo-only ablation at 12 months (85% vs 56%; P = .03). In patients with NICM, no differences were seen between those who underwent epi-endo ablation and those who underwent endo-only ablation at 12 months (36% vs 33%; P = 1.0). In idiopathic VA, only 2 of 17 patients were successfully abated from the epicardium. CONCLUSIONS In this Large tertiary singe-center experience, complication rates are acceptably Low and improved clinical. outcomes were associated with epi-endo ablation in patients with ICM. Patients with NICM represent a growing referred population, although clinical. recurrence remains high despite epicardial ablation. Epicardial ablation has a Low yield in idiopathic VA.
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收藏
页码:490 / 498
页数:9
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