A case of rifampicin-induced haemolysis

被引:5
作者
Sykes, C. A. [1 ]
Shepherd, J. [2 ]
McGoldrick, C. [3 ]
Kennedy, N. [3 ]
Raafat, A. [3 ]
机构
[1] Queen Elizabeth Univ Hosp, Glasgow, Lanark, Scotland
[2] Univ Glasgow, Ctr Virus Res, MRC, Glasgow, Lanark, Scotland
[3] Univ Hosp Monklands, Monkscourt Ave, Airdrie ML6 0JS, Scotland
关键词
drug-induced haemolysis; anti-tuberculosis; acute renal failure;
D O I
10.5588/ijtld.18.0255
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We present a case of pulmonary tuberculosis treated with a rifampicin (RMP) containing regimen, which led to marked haemolysis and acute kidney injury. The patient was shown to have RMP-induced haemolysis on detailed immunological testing. RMP is described as a rare cause of drug-induced haemolysis in the literature. However, it is a widely used drug and this complication may be severe. RMP-induced haemolysis precludes further treatment with the drug. Clinicians should consider this possibility and seek advice if patients on RMP develop haemolysis.
引用
收藏
页码:239 / +
页数:3
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