Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein

被引：115

作者：

Liu, JS ^{[1
]}

Lynch, PA ^{[1
]}

Chien, CY ^{[1
]}

Montelione, GT ^{[1
]}

Krug, RM ^{[1
]}

Berman, HM ^{[1
]}

机构：

[1] RUTGERS STATE UNIV,WRIGHT RIEMAN LABS,DEPT CHEM,PISCATAWAY,NJ 08854

来源：

NATURE STRUCTURAL BIOLOGY | 1997年 / 4卷 / 11期

关键词：

D O I：

10.1038/nsb1197-896

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The nonstructural protein (NS1 protein) of the influenza A virus hinds to several types of RNAs. X-ray crystallographic analysis of the RNA-binding domain reveals a unique topology for the monomer as well as a novel six-helix structure for the dimer.

引用

页码：896 / 899

页数：4

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