Use of triazole-ring formation to attach a Ru/TsDPEN complex for asymmetric transfer hydrogenation to a soluble polymer

被引：18

作者：

Zammit, Charlotte M. ^{[1
]}

Wills, Martin ^{[1
]}

机构：

[1] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England

来源：

TETRAHEDRON-ASYMMETRY | 2013年 / 24卷 / 13-14期

关键词：

POLYETHYLENE-GLYCOL; 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES; RUTHENIUM(II) CATALYST; CLICK CHEMISTRY; KETONES; COMBINATION; BINDING; FUNCTIONALIZATION; ORGANOCATALYSTS; IMMOBILIZATION;

D O I：

10.1016/j.tetasy.2013.05.022

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The cycloaddition of a chiral ligand containing a terminal alkyne to a soluble polymer containing an azide provides a convenient means for the attachment of an asymmetric transfer hydrogenation catalyst to a soluble polymer support. Using these ligands in complexes with Ru(II), gave good results in terms of conversion and enantioselectivity (up to 95% ee) in ketone reduction reactions. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：844 / 852

页数：9

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