Biodegradable magnesium implants for orthopedic applications

被引:262
作者
Waizy, Hazibullah [1 ]
Seitz, Jan-Marten [2 ]
Reifenrath, Janin [3 ]
Weizbauer, Andreas [1 ]
Bach, Friedrich-Wilhelm [2 ]
Meyer-Lindenberg, Andrea [4 ]
Denkena, Berend [5 ]
Windhagen, Henning [1 ]
机构
[1] Hannover Med Sch, Dept Orthopaed Surg, D-30625 Hannover, Germany
[2] Leibniz Univ Hannover, Inst Mat Sci, D-30823 Hannover, Germany
[3] Univ Vet Med Hannover, Small Anim Clin, D-30559 Hannover, Germany
[4] Univ Munich, Fac Vet Med, Ctr Clin Vet Med, Clin Small Anim Surg & Reprod, D-80539 Munich, Germany
[5] Leibnitz Univ Hannover, Inst Prod Engn & Machine Tools IFW, D-30823 Garbsen, Germany
关键词
IN-VIVO CORROSION; RARE-EARTH ALLOY; DEGRADATION BEHAVIOR; MECHANICAL-PROPERTIES; VITRO DEGRADATION; PURE MAGNESIUM; MG-ALLOYS; BIO-CORROSION; PART I; BONE;
D O I
10.1007/s10853-012-6572-2
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The clinical application of degradable orthopedic magnesium implants is a tangible vision in medical science. This interdisciplinary review discusses many different aspects of magnesium alloys comprising the manufacturing process and the latest research. We present the challenges of the manufacturing process of magnesium implants with the risk of contamination with impurities and its effect on corrosion. Furthermore, this paper provides a summary of the current examination methods used in in vitro and in vivo research of magnesium alloys. The influence of various parameters (most importantly the effect of the corrosive media) in in vitro studies and an overview about the current in vivo research is given.
引用
收藏
页码:39 / 50
页数:12
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