The Definition of Open Reading Frame Revisited

被引：52

作者：

Sieber, Patricia ^{[1
]}

Platzer, Matthias ^{[2
]}

Schuster, Stefan ^{[1
]}

机构：

[1] Friedrich Schiller Univ Jena, Dept Bioinformat, Ernst Abbe Pl 2, D-07743 Jena, Germany

[2] Fritz Lipmann Inst, Leibniz Inst Aging, Beutenbergstr 11, D-07745 Jena, Germany

来源：

TRENDS IN GENETICS | 2018年 / 34卷 / 03期

关键词：

PREDICTION; SEQUENCES; GENE;

D O I：

10.1016/j.tig.2017.12.009

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The term open reading frame (ORF) is of central importance to gene finding. Surprisingly, at least three definitions are in use. We discuss several molecular biological and bioinformatics aspects, and we recommend using the definition in which an ORF is bounded by stop codons.

引用

收藏

页码：167 / 170

页数：5

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