A Scalable Synthesis of Chiral Modular Phosphine-Phosphite Ligands

被引：12
|
作者：
Dindaroglu, Mehmet [1 ]
Falk, Anna [1 ]
Schmalz, Hans-Guenther [1 ]
机构：
[1] Univ Cologne, Dept Chem, D-50939 Cologne, Germany
来源：
SYNTHESIS-STUTTGART | 2013年 / 45卷 / 04期
关键词：
Chiral P; P-ligands; enantioselective catalysis; bromine-lithium exchange; synthetic methods; asymmetric 1,4-addition; BIDENTATE CHELATE LIGANDS; CONJUGATE ADDITION; GRIGNARD-REAGENTS; HYDROFORMYLATION; 1,4-ADDITION;
D O I：
10.1055/s-0032-1316847
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The outstanding usefulness of phenol-derived chiral phosphine-phosphite ligands has recently been shown in a number of transition-metal-catalyzed C-C bond-forming reactions. This is exemplified by the synthesis of five new ligands in an optimized procedure that can be reliably performed on a multigram scale.
引用
收藏
页码：527 / 535
页数：9
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