Nanomaterials-based electrochemical immunosensors for cardiac troponin recognition: An illustrated review

被引：60

作者：

Abdorahim, Mojgan ^{[1
]}

Rabiee, Mohammad ^{[1
]}

Alhosseini, Sanaz Naghavi ^{[1
]}

Tahriri, Mohammadreza ^{[1
,2
,3
]}

Yazdanpanah, Sara ^{[1
]}

Alavi, S. Habib ^{[4
]}

Tayebi, Lobat ^{[2
,5
]}

机构：

[1] Amirkabir Univ Technol, Fac Biomed Engn, Biomat Grp, Tehran, Iran

[2] Marquette Univ, Sch Dent, Milwaukee, WI 53201 USA

[3] Univ Tehran Med Sci, Sch Dent, Dent Biomat Dept, Tehran, Iran

[4] Oklahoma State Univ, Sch Mech & Aerosp Engn, Stillwater, OK 74078 USA

[5] Univ Oxford, Dept Engn Sci, Oxford OX1 3PJ, England

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2016年 / 82卷

基金：

美国国家科学基金会;

关键词：

Electrochemical; Biosensor; Cardiac troponin; Acute myocardial infarction; Biomarker; SELF-ASSEMBLED MONOLAYERS; MULTIWALLED CARBON NANOTUBES; SCREEN-PRINTED ELECTRODES; GOLD NANOPARTICLES; LIQUID-CRYSTAL; BIOACTIVE GLASS; BIOSENSOR; SURFACE; GRAPHENE; SENSOR;

D O I：

10.1016/j.trac.2016.06.015

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Cardiac troponins (I and T) have been recommended as the biomarkers of choice for the serological diagnosis and prognosis of Acute Myocardial Infarction (AMI) because of their high sensitivity and specificity. Sensor designing has been developed by nanotechnology revolution presenting faster detection and better reproducibility. This review highlights the nanotechnology impact on electrochemical immunosensor that have been developed for the determination of cardiac troponin and provides an overview of the various types of nano based diagnostic methods, along with significant advances over the last several years in related technologies. It is critically important to diagnose Cardio Vascular Disease (CVD) at early stages of its progression, which allows successful treatment and recovery of patients. Therefore, it is essential to develop simple and sensitive CVD diagnostic methods that can detect cardiac troponin as biomarker based on different types of nanomaterials and their developmental and implicational aspects at very low concentrations in biological fluids. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：337 / 347

页数：11

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