Antibiotic use in children and the use of medicines by parents

被引:6
作者
de Jong, Josta [1 ]
Bos, Jens H. J. [1 ]
de Vries, Tjalling W. [2 ]
de Jong-van den Berg, Lolkje T. W. [1 ]
机构
[1] Univ Groningen, Dept Pharmacoepidemiol & Pharmacoecon, NL-9713 AV Groningen, Netherlands
[2] Med Ctr Leeuwarden, Dept Paediat, Leeuwarden, Netherlands
关键词
PHARMACY DATA; PRESCRIPTION; ASTHMA; FAMILIES; EXPOSURE; CARE; TOOL;
D O I
10.1136/archdischild-2011-301150
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Objective Antibiotic drugs are frequently used for viral infections in children. It is probable that health beliefs and parental concern have great influence on the use of drugs in children. This study, performed in The Netherlands, investigates whether the use of antibiotics in children is associated with the use of medicines by parents. Patients and methods In this observational cohort study, the authors selected 6731 children from the prescription database IADB.nl who did not receive antibiotics until their fifth birthday and 1479 children who received at least one antibiotic prescription every year. The authors then selected parents for each group of children (5790 mothers and 4250 fathers for the children who did not receive antibiotics and 1234 mothers and 1032 fathers for the children who regularly received antibiotics). The authors compared the use of antibiotics and other medicines between the two groups of parents. Results Parents of children who received antibiotics recurrently were found to use more antibiotics themselves compared with parents of children who did not receive antibiotics. Moreover, this group also showed a higher percentage of chronic medication use: (11.3 vs 6.2% (mothers) and 13.1% vs 9.5% (fathers)). Mothers more often use antacids, non-steroidal anti-inflammatory drugs (NSAIDs), analgesics, anxiolytics, hypnotics, antidepressants, drugs for treatment of asthma and antihistamines. Fathers use more antacids, cardiovascular drugs, NSAIDs and asthma drugs. Conclusions The parents of children who receive antibiotic drugs regularly use more medicines compared with the parents of children who use no antibiotic drugs. Parents' medicine use may influence that of children and is a factor physicians and pharmacists should take into account.
引用
收藏
页码:578 / 581
页数:4
相关论文
共 19 条
[1]   More physician consultations and antibiotic prescriptions in families with high concern about infectious illness-adequate response to infection-prone child or self-fulfilling prophecy? [J].
Andre, Malin ;
Hedin, Katarina ;
Hakansson, Anders ;
Moelstad, Sigvard ;
Rodhe, Nils ;
Petersson, Christer .
FAMILY PRACTICE, 2007, 24 (04) :302-307
[2]   Antibiotic prescription in Italian children: a population-based study in Friuli Venezia Giulia, north-east Italy [J].
Borgnolo, G ;
Simon, G ;
Francescutti, C ;
Lattuada, L ;
Zanier, L .
ACTA PAEDIATRICA, 2001, 90 (11) :1316-1320
[3]   Variation in antibiotic use in the European Union [J].
Cars, O ;
Mölstad, S ;
Melander, A .
LANCET, 2001, 357 (9271) :1851-1853
[4]   Coprescription of Antibiotics and Asthma Drugs in Children [J].
De Boeck, Kris ;
Vermeulen, Francois ;
Meyts, Isabelle ;
Hutsebaut, Luc ;
Franckaert, Danny ;
Proesmans, Marijke .
PEDIATRICS, 2011, 127 (06) :1022-1026
[5]   Respiratory symptoms in young infancy: child, parent and physician related determinants of drug prescription in primary care [J].
de Jong, Brita M. ;
van der Ent, Cornelis K. ;
van der Zalm, Marieke M. ;
van Putte-Katier, Nienke ;
Verheij, Theo J. M. ;
Kimpen, Jan L. L. ;
Uiterwaal, Cuno S. P. M. .
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 2009, 18 (07) :610-618
[6]   Antibiotic drug use of children in the Netherlands from 1999 till 2005 [J].
de Jong, Josta ;
van den Berg, Paul B. ;
de Vries, Tjalling W. ;
de Jong-van den Berg, Lolkje T. W. .
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2008, 64 (09) :913-919
[7]   Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. [J].
Goossens, H ;
Ferech, M ;
Stichele, RV ;
Elseviers, M .
LANCET, 2005, 365 (9459) :579-587
[8]   Evidence-based prescribing of antibiotics for children: role of socioeconomic status and physician characteristics [J].
Kozyrskyj, AL ;
Dahl, ME ;
Chateau, DG ;
Mazowita, GB ;
Klassen, TP ;
Law, BJ .
CANADIAN MEDICAL ASSOCIATION JOURNAL, 2004, 171 (02) :139-145
[9]   Recurrent antibiotic use in a small child and the effects on the family [J].
Louhi-Pirkanniemi, K ;
Rautava, P ;
Aromaa, M ;
Ojanlatva, A ;
Mertsola, J ;
Helenius, H ;
Sillanpää, M .
SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE, 2004, 22 (01) :16-21
[10]   Antibiotic Prescription With Asthma Medications: Why Is It So Common? [J].
Mangione-Smith, Rita ;
Krogstad, Paul .
PEDIATRICS, 2011, 127 (06) :1174-1176