Populeuphrines A and B, two new cembrane diterpenoids from the resins of Populus euphratica

被引：8

作者：

Liu, Kai-Xin ^{[1
]}

Qin, Da-Peng ^{[2
]}

Zhu, Yan-Xia ^{[3
]}

Wang, Shao-Xiang ^{[2
]}

Jiao, Ya-Bin ^{[2
]}

Ge, Peng-Ling ^{[1
]}

Cheng, Yong-Xian ^{[2
]}

机构：

[1] Heilongjiang Univ Chinese Med, Dept Pharmacol, Sch Basic Med Sci, Harbin 150040, Heilongjiang, Peoples R China

[2] Shenzhen Univ, Hlth Sci Ctr, Sch Pharmaceut Sci, Shenzhen 518060, Peoples R China

[3] Shenzhen Univ, Hlth Sci Ctr, Sch Basic Med, Shenzhen, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2020年 / 34卷 / 21期

关键词：

Diversifolious poplar resin; Salicaceae; cembrane diterpenoids; quantum chemical computation; biological evaluation; GUM-RESIN; BOSWELLIA-CARTERII; TERPENOIDS;

D O I：

10.1080/14786419.2019.1610753

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two new cembrane diterpenoids, named populeuphrines A and B (1 and 2), together with three known analogues (3-5) were isolated from the resins of Populus euphratica. The planar structures and relative configurations of 1 and 2 were elucidated by detailed 1 D and 2 D NMR spectroscopic analyses. The absolute configurations of 1 and 2 were determined by X-ray diffraction analysis and quantum chemical computation. Biological activities of all the isolates against proliferation of human cancer cells and umbilical cord mesenchymal stem cells were evaluated. [GRAPHICS] .

引用

页码：3108 / 3116

页数：9

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