The human complement receptor type 2 (CR2)/CR1 fusion protein TT32, a targeted inhibitor of the classical and alternative pathway C3 convertases, prevents arthritis in active immunization and passive transfer models and acts by CR2-dependent targeting of CR1 regulatory activity

被引：6

作者：

Holers, Michael ^{[1
]}

Banda, Nirmal ^{[1
]}

Mehta, Gaurav ^{[1
]}

Fridkis-Hareli, Masha ^{[2
,3
]}

Or, Eran ^{[2
,3
]}

Storek, Michael ^{[2
,3
]}

Altman, Richard ^{[2
,3
]}

Johnson, Krista ^{[2
,3
]}

Katti, Suresh ^{[2
,3
]}

机构：

[1] Univ Colorado, Sch Med, Dept Med, Aurora, CO USA

[2] Alex Pharmaceut, Cambridge, MA USA

[3] Alex Pharmaceut, Cheshire, CT USA

来源：

关键词：

D O I：

10.1016/j.imbio.2012.08.232

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

230

引用

页码：1210 / 1210

页数：1