De-risking the clinical development of cholesteryl ester transfer protein inhibitors: how much is good enough?

被引:6
作者
Arsenault, Benoit J. [2 ]
Boekholdt, S. Matthijs [3 ]
Tardif, Jean-Claude [2 ]
Kastelein, John J. P. [1 ]
机构
[1] Univ Amsterdam, Acad Med Ctr, Dept Vasc Med, NL-1105 AZ Amsterdam, Netherlands
[2] Univ Montreal, Montreal Heart Inst, Quebec City, PQ, Canada
[3] Univ Amsterdam, Acad Med Ctr, Dept Cardiol, NL-1105 AZ Amsterdam, Netherlands
关键词
OFF-TARGET TOXICITY; ENDOTHELIAL DYSFUNCTION; TORCETRAPIB; ALDOSTERONE; DISEASE; SAFETY;
D O I
10.1093/eurheartj/ehr408
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1548 / 1550
页数:3
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